Percentage of Hemoglobin A1C(HbA1c) as an Indicator of Pre-Diabetic Condition in Impaired Glucose Level Patients

Binay Kumar Raut; Mukesh Kumar Jha; Sapana Koju; Kishor Khanal; Shyam Sundar Malla

doi:doi:10.11648/j.ajim.20140204.11

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Percentage of Hemoglobin A1C(HbA1c) as an Indicator of Pre-Diabetic Condition in Impaired Glucose Level Patients

Binay Kumar Raut, Mukesh Kumar Jha, Sapana Koju, Kishor Khanal, Shyam Sundar Malla

Published in American Journal of Internal Medicine (Volume 2, Issue 4)

Received: 16 June 2014 Accepted: 28 June 2014 Published: 30 June 2014

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Abstract

Background: The high prevalence of diabetes mellitus has emerged as a worldwide public health problem in the past 20 years. Type 2 diabetes is the most common form of diabetes, estimated to account for 85–90% of diabetes. Hemoglobin A(1c) (HbA1c) has been widely used as a clinically important assessment tool for outcome analyses related to glycemic control. The HbA1c test has been shown to predict the risk for the development of many of the chronic complications in diabetes. Objectives: The study was undertaken to find out if HbA1c levels can be used as indicator of the pre-diabetic condition in patients with impaired blood sugar levels around Kathmandu valley and to find out the percentage of HbA1c in those patients. Also a correlation analysis with impaired fasting glucose (IFG) and impaired glucose tolerance (IGT) levels was carried out. Methods: The study was conducted in the Department of Biochemistry, Kathmandu University School of Medical Sciences. A total of 102 patients with impaired blood glucose levels participated in the study. Estimation of HbA1c was performed by using a commercial NycoCard Kit, a rapid in vitro test for the measurement of glycated hemoglobin in human blood. Results: The mean % of HbA1c was found to be 6.44902 amongst the 102 patients and no correlation was found to be observed between HbA1c with IFG and IGT values. Conclusion: In conclusion HbA1c % proved to be a valuable indicator of the pre-diabetic condition and could contribute to understanding the role of the various risk factors of dietary, social and physical nature in the development of diabetes.

Published in	American Journal of Internal Medicine (Volume 2, Issue 4)
DOI	10.11648/j.ajim.20140204.11
Page(s)	59-62
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2014. Published by Science Publishing Group

Keywords

Diabetes Mellitus, HbA1C, Impaired Fasting Glucose (IFG)

References

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APA Style

Binay Kumar Raut, Mukesh Kumar Jha, Sapana Koju, Kishor Khanal, Shyam Sundar Malla. (2014). Percentage of Hemoglobin A1C(HbA1c) as an Indicator of Pre-Diabetic Condition in Impaired Glucose Level Patients. American Journal of Internal Medicine, 2(4), 59-62. https://doi.org/10.11648/j.ajim.20140204.11

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ACS Style

Binay Kumar Raut; Mukesh Kumar Jha; Sapana Koju; Kishor Khanal; Shyam Sundar Malla. Percentage of Hemoglobin A1C(HbA1c) as an Indicator of Pre-Diabetic Condition in Impaired Glucose Level Patients. Am. J. Intern. Med. 2014, 2(4), 59-62. doi: 10.11648/j.ajim.20140204.11

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AMA Style

Binay Kumar Raut, Mukesh Kumar Jha, Sapana Koju, Kishor Khanal, Shyam Sundar Malla. Percentage of Hemoglobin A1C(HbA1c) as an Indicator of Pre-Diabetic Condition in Impaired Glucose Level Patients. Am J Intern Med. 2014;2(4):59-62. doi: 10.11648/j.ajim.20140204.11

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@article{10.11648/j.ajim.20140204.11,
  author = {Binay Kumar Raut and Mukesh Kumar Jha and Sapana Koju and Kishor Khanal and Shyam Sundar Malla},
  title = {Percentage of Hemoglobin A1C(HbA1c) as an Indicator of Pre-Diabetic Condition in Impaired Glucose Level Patients},
  journal = {American Journal of Internal Medicine},
  volume = {2},
  number = {4},
  pages = {59-62},
  doi = {10.11648/j.ajim.20140204.11},
  url = {https://doi.org/10.11648/j.ajim.20140204.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajim.20140204.11},
  abstract = {Background: The high prevalence of diabetes mellitus has emerged as a worldwide public health problem in the past 20 years. Type 2 diabetes is the most common form of diabetes, estimated to account for 85–90% of diabetes. Hemoglobin A(1c) (HbA1c) has been widely used as a clinically important assessment tool for outcome analyses related to glycemic control. The HbA1c test has been shown to predict the risk for the development of many of the chronic complications in diabetes. Objectives: The study was undertaken to find out if HbA1c levels can be used as indicator of the pre-diabetic condition in patients with impaired blood sugar levels around Kathmandu valley and to find out the percentage of HbA1c in those patients. Also a correlation analysis with impaired fasting glucose (IFG) and impaired glucose tolerance (IGT) levels was carried out. Methods: The study was conducted in the Department of Biochemistry, Kathmandu University School of Medical Sciences. A total of 102 patients with impaired blood glucose levels participated in the study. Estimation of HbA1c was performed by using a commercial NycoCard Kit, a rapid in vitro test for the measurement of glycated hemoglobin in human blood. Results: The mean % of HbA1c was found to be 6.44902 amongst the 102 patients and no correlation was found to be observed between HbA1c with IFG and IGT values. Conclusion: In conclusion HbA1c % proved to be a valuable indicator of the pre-diabetic condition and could contribute to understanding the role of the various risk factors of dietary, social and physical nature in the development of diabetes.},
 year = {2014}
}

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TY  - JOUR
T1  - Percentage of Hemoglobin A1C(HbA1c) as an Indicator of Pre-Diabetic Condition in Impaired Glucose Level Patients
AU  - Binay Kumar Raut
AU  - Mukesh Kumar Jha
AU  - Sapana Koju
AU  - Kishor Khanal
AU  - Shyam Sundar Malla
Y1  - 2014/06/30
PY  - 2014
N1  - https://doi.org/10.11648/j.ajim.20140204.11
DO  - 10.11648/j.ajim.20140204.11
T2  - American Journal of Internal Medicine
JF  - American Journal of Internal Medicine
JO  - American Journal of Internal Medicine
SP  - 59
EP  - 62
PB  - Science Publishing Group
SN  - 2330-4324
UR  - https://doi.org/10.11648/j.ajim.20140204.11
AB  - Background: The high prevalence of diabetes mellitus has emerged as a worldwide public health problem in the past 20 years. Type 2 diabetes is the most common form of diabetes, estimated to account for 85–90% of diabetes. Hemoglobin A(1c) (HbA1c) has been widely used as a clinically important assessment tool for outcome analyses related to glycemic control. The HbA1c test has been shown to predict the risk for the development of many of the chronic complications in diabetes. Objectives: The study was undertaken to find out if HbA1c levels can be used as indicator of the pre-diabetic condition in patients with impaired blood sugar levels around Kathmandu valley and to find out the percentage of HbA1c in those patients. Also a correlation analysis with impaired fasting glucose (IFG) and impaired glucose tolerance (IGT) levels was carried out. Methods: The study was conducted in the Department of Biochemistry, Kathmandu University School of Medical Sciences. A total of 102 patients with impaired blood glucose levels participated in the study. Estimation of HbA1c was performed by using a commercial NycoCard Kit, a rapid in vitro test for the measurement of glycated hemoglobin in human blood. Results: The mean % of HbA1c was found to be 6.44902 amongst the 102 patients and no correlation was found to be observed between HbA1c with IFG and IGT values. Conclusion: In conclusion HbA1c % proved to be a valuable indicator of the pre-diabetic condition and could contribute to understanding the role of the various risk factors of dietary, social and physical nature in the development of diabetes.
VL  - 2
IS  - 4
ER  -

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Author Information

Binay Kumar Raut

Department of Biochemistry, Kathmandu University School of Medical Sciences, Dhulikhel, Kavre, Nepal
Mukesh Kumar Jha

Department of Physiology, Kathmandu University School of Medical Sciences, Dhulikhel, Kavre, Nepal
Sapana Koju

Faculty of Human Biology, Kathmandu University School of Medical Sciences, Dhulikhel, Kavre, Nepal
Kishor Khanal

Department of Community Medicine, Kathmandu University School of Medical Sciences, Kavre, Nepal
Shyam Sundar Malla

Department of Biochemistry, Kathmandu University School of Medical Sciences, Dhulikhel, Kavre, Nepal

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APA Style

Binay Kumar Raut, Mukesh Kumar Jha, Sapana Koju, Kishor Khanal, Shyam Sundar Malla. (2014). Percentage of Hemoglobin A1C(HbA1c) as an Indicator of Pre-Diabetic Condition in Impaired Glucose Level Patients. American Journal of Internal Medicine, 2(4), 59-62. https://doi.org/10.11648/j.ajim.20140204.11

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ACS Style

Binay Kumar Raut; Mukesh Kumar Jha; Sapana Koju; Kishor Khanal; Shyam Sundar Malla. Percentage of Hemoglobin A1C(HbA1c) as an Indicator of Pre-Diabetic Condition in Impaired Glucose Level Patients. Am. J. Intern. Med. 2014, 2(4), 59-62. doi: 10.11648/j.ajim.20140204.11

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AMA Style

Binay Kumar Raut, Mukesh Kumar Jha, Sapana Koju, Kishor Khanal, Shyam Sundar Malla. Percentage of Hemoglobin A1C(HbA1c) as an Indicator of Pre-Diabetic Condition in Impaired Glucose Level Patients. Am J Intern Med. 2014;2(4):59-62. doi: 10.11648/j.ajim.20140204.11

Copy | Download

@article{10.11648/j.ajim.20140204.11,
  author = {Binay Kumar Raut and Mukesh Kumar Jha and Sapana Koju and Kishor Khanal and Shyam Sundar Malla},
  title = {Percentage of Hemoglobin A1C(HbA1c) as an Indicator of Pre-Diabetic Condition in Impaired Glucose Level Patients},
  journal = {American Journal of Internal Medicine},
  volume = {2},
  number = {4},
  pages = {59-62},
  doi = {10.11648/j.ajim.20140204.11},
  url = {https://doi.org/10.11648/j.ajim.20140204.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajim.20140204.11},
  abstract = {Background: The high prevalence of diabetes mellitus has emerged as a worldwide public health problem in the past 20 years. Type 2 diabetes is the most common form of diabetes, estimated to account for 85–90% of diabetes. Hemoglobin A(1c) (HbA1c) has been widely used as a clinically important assessment tool for outcome analyses related to glycemic control. The HbA1c test has been shown to predict the risk for the development of many of the chronic complications in diabetes. Objectives: The study was undertaken to find out if HbA1c levels can be used as indicator of the pre-diabetic condition in patients with impaired blood sugar levels around Kathmandu valley and to find out the percentage of HbA1c in those patients. Also a correlation analysis with impaired fasting glucose (IFG) and impaired glucose tolerance (IGT) levels was carried out. Methods: The study was conducted in the Department of Biochemistry, Kathmandu University School of Medical Sciences. A total of 102 patients with impaired blood glucose levels participated in the study. Estimation of HbA1c was performed by using a commercial NycoCard Kit, a rapid in vitro test for the measurement of glycated hemoglobin in human blood. Results: The mean % of HbA1c was found to be 6.44902 amongst the 102 patients and no correlation was found to be observed between HbA1c with IFG and IGT values. Conclusion: In conclusion HbA1c % proved to be a valuable indicator of the pre-diabetic condition and could contribute to understanding the role of the various risk factors of dietary, social and physical nature in the development of diabetes.},
 year = {2014}
}

Copy | Download

TY  - JOUR
T1  - Percentage of Hemoglobin A1C(HbA1c) as an Indicator of Pre-Diabetic Condition in Impaired Glucose Level Patients
AU  - Binay Kumar Raut
AU  - Mukesh Kumar Jha
AU  - Sapana Koju
AU  - Kishor Khanal
AU  - Shyam Sundar Malla
Y1  - 2014/06/30
PY  - 2014
N1  - https://doi.org/10.11648/j.ajim.20140204.11
DO  - 10.11648/j.ajim.20140204.11
T2  - American Journal of Internal Medicine
JF  - American Journal of Internal Medicine
JO  - American Journal of Internal Medicine
SP  - 59
EP  - 62
PB  - Science Publishing Group
SN  - 2330-4324
UR  - https://doi.org/10.11648/j.ajim.20140204.11
AB  - Background: The high prevalence of diabetes mellitus has emerged as a worldwide public health problem in the past 20 years. Type 2 diabetes is the most common form of diabetes, estimated to account for 85–90% of diabetes. Hemoglobin A(1c) (HbA1c) has been widely used as a clinically important assessment tool for outcome analyses related to glycemic control. The HbA1c test has been shown to predict the risk for the development of many of the chronic complications in diabetes. Objectives: The study was undertaken to find out if HbA1c levels can be used as indicator of the pre-diabetic condition in patients with impaired blood sugar levels around Kathmandu valley and to find out the percentage of HbA1c in those patients. Also a correlation analysis with impaired fasting glucose (IFG) and impaired glucose tolerance (IGT) levels was carried out. Methods: The study was conducted in the Department of Biochemistry, Kathmandu University School of Medical Sciences. A total of 102 patients with impaired blood glucose levels participated in the study. Estimation of HbA1c was performed by using a commercial NycoCard Kit, a rapid in vitro test for the measurement of glycated hemoglobin in human blood. Results: The mean % of HbA1c was found to be 6.44902 amongst the 102 patients and no correlation was found to be observed between HbA1c with IFG and IGT values. Conclusion: In conclusion HbA1c % proved to be a valuable indicator of the pre-diabetic condition and could contribute to understanding the role of the various risk factors of dietary, social and physical nature in the development of diabetes.
VL  - 2
IS  - 4
ER  -

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