Left Atrial Size and Risk of Stroke in Patients with Sinus Rhythm and Normal Left Ventricular Systolic Function

Hanan K. Altalhi; Asgad A. Abdalgbar; Ali Areef Fadhlullah

doi:doi:10.11648/j.ajim.20160406.14

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Left Atrial Size and Risk of Stroke in Patients with Sinus Rhythm and Normal Left Ventricular Systolic Function

Hanan K. Altalhi, Asgad A. Abdalgbar, Ali Areef Fadhlullah

Published in American Journal of Internal Medicine (Volume 4, Issue 6)

Received: 21 October 2016 Accepted: 2 November 2016 Published: 25 November 2016

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Abstract

Increased left atrial (L A) size associated with poor cardiovascular outcome such as development of heart failure, atrial fibrillation (AF) and stroke in the elderly. Objective: The present study was conducted to reevaluate the relationship between la size and stroke in subjects of all ages, not just the elderly who presented with preserved left ventricular systolic function (lvsf) and sinus rhythm (sr). Patients and Methods: This is case control study of 52 patients admitted to the hospital 26 with diagnosis of ischemic stroke (case subject), and 26 patients without ischemic stroke were included as (control subject). The diagnosis of Cerebral infarction was confirmed by a new computer Tomography of Brain All participant underwent the standard examination and testing as well as Echocardiography (measurement of left atrial dimension, Ejection Fraction,Mitral inflow, LV mass), patients with valvular heart disease, atrial fibrillation or coronary disease were excluded. Result: The mean age was 69 ± 18 years in the stroke group and 66 ± 17 years in control group. The LA dimension of stroke group (3.38 ± 0.50 cm) was significantly greater than that of the control group (3.56 ± 0.44cm); P< 0.0001) E&A Velocity showed no significant relation with Stroke (p=NS) Left ventricular mass, left ventricular mass / height and left ventricular mass index were significantly related to stroke (p<0.0001, p= 0.001, p = 0.001, respectively). Conclusion: Echocardiographic left atrial enlargement has prognostic value in identifying a subset of persons at increased risk of stroke.

Published in	American Journal of Internal Medicine (Volume 4, Issue 6)
DOI	10.11648/j.ajim.20160406.14
Page(s)	113-116
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2016. Published by Science Publishing Group

Keywords

Left Atrial Size (La), Left Ventricular Systolic Function (Lvsf) Sinus Rhythm (Sr), Stroke Left Ventricular Mass Index (Lvmi), Echocardiography (Echo)

References

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[2]	Barnes ME, Miyasaka Y, Seward JB, et al. Left atrial volume in the prediction of first ischemic stroke in an elderly cohort without atrial fibrillation. Mayo Clin Proc. 2004; 791008-1014.
[3]	Basnight MA, Gonzales MS, Keshenovich SC, Appleton CP. Pulmonary venous flow velocity: relation to hemodynamics, mitral flow velocity and left atrial volume, and ejection fraction. J Am Soc Echocardiogr. 1991; 4: 547-558.
[4]	Benjamin EJ, D A gostino RB, Belanger AJ, Wolf PA, Levy D. Left atrial size and the risk of stroke and death. Circulation. 1995; 92: 835-841.
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[6]	6evereux RB, Alonso DR, Lutas EM, et al. Echocardiographic assessment of left ventricular hypertrophy: comparison to necropsy findings. Am J Cardio. 1986; 57: 450-458.
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[9]	Lang RM, Bierig M, Devereux RB, et al Recommendation for chamber quantification are part from the American society of Echocardiography and standard committee and chamber quantification writing group, developed in conjunction with European Association of Echocardiography A branch of European society of Cardiology Jam soc Echocardiography 2005; 18: 1440-63.
[10]	Lee RJ, Bartzokis T, Yeoh TK, Grogin HR, Choi D, Schnittger I. Enhanced detection of intra cardiac sources of cerebral emboli by trans esophageal echocardiograph. Stroke. 1991; 22: 734-739.
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[12]	Miller JT, O Rourke RA, Crawford MH. Left atrial enlargement: an early sign of hypertensive heart disease Am Heart J. 1988; 116: 1048-1051.
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[14]	Oh JK, Appleton CP,Hatle LK, Nishimura RA, Seward JB, Tajik AJ. The noninvasive assessment of left ventricular diastolic function with two-dimensional and Doppler echocardiography. J Am Soc Echocardioger.1997; 10: 246-270.
[15]	Tsang SM, Barnes ME, Gersh BJ, Bailey KR, Seward JB. Left atrial volume as a morphophysiologic expression of left ventricular diastolic dysfunction and relation to cardiovascular risk burden. Am J Cardiol.2002; 90: 1284-1289.
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APA Style

Hanan K. Altalhi, Asgad A. Abdalgbar, Ali Areef Fadhlullah. (2016). Left Atrial Size and Risk of Stroke in Patients with Sinus Rhythm and Normal Left Ventricular Systolic Function. American Journal of Internal Medicine, 4(6), 113-116. https://doi.org/10.11648/j.ajim.20160406.14

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ACS Style

Hanan K. Altalhi; Asgad A. Abdalgbar; Ali Areef Fadhlullah. Left Atrial Size and Risk of Stroke in Patients with Sinus Rhythm and Normal Left Ventricular Systolic Function. Am. J. Intern. Med. 2016, 4(6), 113-116. doi: 10.11648/j.ajim.20160406.14

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AMA Style

Hanan K. Altalhi, Asgad A. Abdalgbar, Ali Areef Fadhlullah. Left Atrial Size and Risk of Stroke in Patients with Sinus Rhythm and Normal Left Ventricular Systolic Function. Am J Intern Med. 2016;4(6):113-116. doi: 10.11648/j.ajim.20160406.14

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@article{10.11648/j.ajim.20160406.14,
  author = {Hanan K. Altalhi and Asgad A. Abdalgbar and Ali Areef Fadhlullah},
  title = {Left Atrial Size and Risk of Stroke in Patients with Sinus Rhythm and Normal Left Ventricular Systolic Function},
  journal = {American Journal of Internal Medicine},
  volume = {4},
  number = {6},
  pages = {113-116},
  doi = {10.11648/j.ajim.20160406.14},
  url = {https://doi.org/10.11648/j.ajim.20160406.14},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajim.20160406.14},
  abstract = {Increased left atrial (L A) size associated with poor cardiovascular outcome such as development of heart failure, atrial fibrillation (AF) and stroke in the elderly. Objective: The present study was conducted to reevaluate the relationship between la size and stroke in subjects of all ages, not just the elderly who presented with preserved left ventricular systolic function (lvsf) and sinus rhythm (sr). Patients and Methods: This is case control study of 52 patients admitted to the hospital 26 with diagnosis of ischemic stroke (case subject), and 26 patients without ischemic stroke were included as (control subject). The diagnosis of Cerebral infarction was confirmed by a new computer Tomography of Brain All participant underwent the standard examination and testing as well as Echocardiography (measurement of left atrial dimension, Ejection Fraction,Mitral inflow, LV mass), patients with valvular heart disease, atrial fibrillation or coronary disease were excluded. Result: The mean age was 69 ± 18 years in the stroke group and 66 ± 17 years in control group. The LA dimension of stroke group (3.38 ± 0.50 cm) was significantly greater than that of the control group (3.56 ± 0.44cm); P< 0.0001) E&A Velocity showed no significant relation with Stroke (p=NS) Left ventricular mass, left ventricular mass / height and left ventricular mass index were significantly related to stroke (p<0.0001, p= 0.001, p = 0.001, respectively). Conclusion: Echocardiographic left atrial enlargement has prognostic value in identifying a subset of persons at increased risk of stroke.},
 year = {2016}
}

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TY  - JOUR
T1  - Left Atrial Size and Risk of Stroke in Patients with Sinus Rhythm and Normal Left Ventricular Systolic Function
AU  - Hanan K. Altalhi
AU  - Asgad A. Abdalgbar
AU  - Ali Areef Fadhlullah
Y1  - 2016/11/25
PY  - 2016
N1  - https://doi.org/10.11648/j.ajim.20160406.14
DO  - 10.11648/j.ajim.20160406.14
T2  - American Journal of Internal Medicine
JF  - American Journal of Internal Medicine
JO  - American Journal of Internal Medicine
SP  - 113
EP  - 116
PB  - Science Publishing Group
SN  - 2330-4324
UR  - https://doi.org/10.11648/j.ajim.20160406.14
AB  - Increased left atrial (L A) size associated with poor cardiovascular outcome such as development of heart failure, atrial fibrillation (AF) and stroke in the elderly. Objective: The present study was conducted to reevaluate the relationship between la size and stroke in subjects of all ages, not just the elderly who presented with preserved left ventricular systolic function (lvsf) and sinus rhythm (sr). Patients and Methods: This is case control study of 52 patients admitted to the hospital 26 with diagnosis of ischemic stroke (case subject), and 26 patients without ischemic stroke were included as (control subject). The diagnosis of Cerebral infarction was confirmed by a new computer Tomography of Brain All participant underwent the standard examination and testing as well as Echocardiography (measurement of left atrial dimension, Ejection Fraction,Mitral inflow, LV mass), patients with valvular heart disease, atrial fibrillation or coronary disease were excluded. Result: The mean age was 69 ± 18 years in the stroke group and 66 ± 17 years in control group. The LA dimension of stroke group (3.38 ± 0.50 cm) was significantly greater than that of the control group (3.56 ± 0.44cm); P< 0.0001) E&A Velocity showed no significant relation with Stroke (p=NS) Left ventricular mass, left ventricular mass / height and left ventricular mass index were significantly related to stroke (p<0.0001, p= 0.001, p = 0.001, respectively). Conclusion: Echocardiographic left atrial enlargement has prognostic value in identifying a subset of persons at increased risk of stroke.
VL  - 4
IS  - 6
ER  -

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Author Information

Hanan K. Altalhi

Faculty of Medicine, University of Omar El mukhtar, Albayda, Libya
Asgad A. Abdalgbar

Faculty of Medicine, University of Omar El mukhtar, Albayda, Libya
Ali Areef Fadhlullah

Faculty of Medicine, University of Omar El mukhtar, Albayda, Libya

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APA Style

Hanan K. Altalhi, Asgad A. Abdalgbar, Ali Areef Fadhlullah. (2016). Left Atrial Size and Risk of Stroke in Patients with Sinus Rhythm and Normal Left Ventricular Systolic Function. American Journal of Internal Medicine, 4(6), 113-116. https://doi.org/10.11648/j.ajim.20160406.14

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ACS Style

Hanan K. Altalhi; Asgad A. Abdalgbar; Ali Areef Fadhlullah. Left Atrial Size and Risk of Stroke in Patients with Sinus Rhythm and Normal Left Ventricular Systolic Function. Am. J. Intern. Med. 2016, 4(6), 113-116. doi: 10.11648/j.ajim.20160406.14

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AMA Style

Hanan K. Altalhi, Asgad A. Abdalgbar, Ali Areef Fadhlullah. Left Atrial Size and Risk of Stroke in Patients with Sinus Rhythm and Normal Left Ventricular Systolic Function. Am J Intern Med. 2016;4(6):113-116. doi: 10.11648/j.ajim.20160406.14

Copy | Download

@article{10.11648/j.ajim.20160406.14,
  author = {Hanan K. Altalhi and Asgad A. Abdalgbar and Ali Areef Fadhlullah},
  title = {Left Atrial Size and Risk of Stroke in Patients with Sinus Rhythm and Normal Left Ventricular Systolic Function},
  journal = {American Journal of Internal Medicine},
  volume = {4},
  number = {6},
  pages = {113-116},
  doi = {10.11648/j.ajim.20160406.14},
  url = {https://doi.org/10.11648/j.ajim.20160406.14},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajim.20160406.14},
  abstract = {Increased left atrial (L A) size associated with poor cardiovascular outcome such as development of heart failure, atrial fibrillation (AF) and stroke in the elderly. Objective: The present study was conducted to reevaluate the relationship between la size and stroke in subjects of all ages, not just the elderly who presented with preserved left ventricular systolic function (lvsf) and sinus rhythm (sr). Patients and Methods: This is case control study of 52 patients admitted to the hospital 26 with diagnosis of ischemic stroke (case subject), and 26 patients without ischemic stroke were included as (control subject). The diagnosis of Cerebral infarction was confirmed by a new computer Tomography of Brain All participant underwent the standard examination and testing as well as Echocardiography (measurement of left atrial dimension, Ejection Fraction,Mitral inflow, LV mass), patients with valvular heart disease, atrial fibrillation or coronary disease were excluded. Result: The mean age was 69 ± 18 years in the stroke group and 66 ± 17 years in control group. The LA dimension of stroke group (3.38 ± 0.50 cm) was significantly greater than that of the control group (3.56 ± 0.44cm); P< 0.0001) E&A Velocity showed no significant relation with Stroke (p=NS) Left ventricular mass, left ventricular mass / height and left ventricular mass index were significantly related to stroke (p<0.0001, p= 0.001, p = 0.001, respectively). Conclusion: Echocardiographic left atrial enlargement has prognostic value in identifying a subset of persons at increased risk of stroke.},
 year = {2016}
}

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TY  - JOUR
T1  - Left Atrial Size and Risk of Stroke in Patients with Sinus Rhythm and Normal Left Ventricular Systolic Function
AU  - Hanan K. Altalhi
AU  - Asgad A. Abdalgbar
AU  - Ali Areef Fadhlullah
Y1  - 2016/11/25
PY  - 2016
N1  - https://doi.org/10.11648/j.ajim.20160406.14
DO  - 10.11648/j.ajim.20160406.14
T2  - American Journal of Internal Medicine
JF  - American Journal of Internal Medicine
JO  - American Journal of Internal Medicine
SP  - 113
EP  - 116
PB  - Science Publishing Group
SN  - 2330-4324
UR  - https://doi.org/10.11648/j.ajim.20160406.14
AB  - Increased left atrial (L A) size associated with poor cardiovascular outcome such as development of heart failure, atrial fibrillation (AF) and stroke in the elderly. Objective: The present study was conducted to reevaluate the relationship between la size and stroke in subjects of all ages, not just the elderly who presented with preserved left ventricular systolic function (lvsf) and sinus rhythm (sr). Patients and Methods: This is case control study of 52 patients admitted to the hospital 26 with diagnosis of ischemic stroke (case subject), and 26 patients without ischemic stroke were included as (control subject). The diagnosis of Cerebral infarction was confirmed by a new computer Tomography of Brain All participant underwent the standard examination and testing as well as Echocardiography (measurement of left atrial dimension, Ejection Fraction,Mitral inflow, LV mass), patients with valvular heart disease, atrial fibrillation or coronary disease were excluded. Result: The mean age was 69 ± 18 years in the stroke group and 66 ± 17 years in control group. The LA dimension of stroke group (3.38 ± 0.50 cm) was significantly greater than that of the control group (3.56 ± 0.44cm); P< 0.0001) E&A Velocity showed no significant relation with Stroke (p=NS) Left ventricular mass, left ventricular mass / height and left ventricular mass index were significantly related to stroke (p<0.0001, p= 0.001, p = 0.001, respectively). Conclusion: Echocardiographic left atrial enlargement has prognostic value in identifying a subset of persons at increased risk of stroke.
VL  - 4
IS  - 6
ER  -

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