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Clinical and Morphological Features of Primary Pulmonary Hypertension: The Analysis of Two Cases from Practice

Received: 1 April 2017     Accepted: 18 May 2017     Published: 26 October 2017
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Abstract

Primary pulmonary hypertension is a rare disease of unknown etiology, which is diagnosed in cases when examination of the patient with high blood pressure in the pulmonary artery does not allow determining its causes. The authors of this article analyze the literature data about primary pulmonary hypertension and report two cases from practice of this pathology. In one case of autopsy of 32-year-old woman primary pulmonary hypertension has been established during the investigation of autopsy material and in another case of autopsy of 52-year-old man this disease has been diagnosed during life. The description of the current state of the problem of primary pulmonary hypertension will be interesting to doctors of any specialization and will also allow to improve of physicians knowledge about this pathology.

Published in American Journal of Internal Medicine (Volume 5, Issue 6)
DOI 10.11648/j.ajim.20170506.11
Page(s) 112-116
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2017. Published by Science Publishing Group

Keywords

Primary Pulmonary Hypertension, Clinical and Morphological Features, Cases from Practice, Literature Review

References
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[2] Firth AL, Mandel J, Yuan J X-J Idiopathic pulmonary arterial hypertension. DMM. 2010; 3: 268-273.
[3] Efremova OA, Logvinenko SI, Bocharova MA, Gubareva NA Rare case in practice of physician – primary pulmonary hypertension. Scientific reviewing journal (Medicine. Pharmacy). 2011; 22 (117) (16): 281-284.
[4] Humbert M, Souza R, Simonneau G Idiopathic pulmonary arterial hypertension and its prognosis in the modern management era in developed and developing countries. Pulmonary Vascular Disorders. 2012; 41: 85-93.
[5] Hoette S, Jardim C, Souza D Diagnosis and treatment of pulmonary hypertension: an update. J Bras Pneumol. 2010; 36 (6): 795-811.
[6] Camm AJ, Lüscher TF, Serruys PW, editors. The ESC Textbook of Cardiovascular Medicine. 2nd ed. Oxford: Oxford University Press; 2009. 1398 p.
[7] Paltsev MA, Kaktursky LV, Zairatyants OV, editors. Pathological anatomy: national leadership. Moscow: GEOTAR Media; 2011. 1264 p.
[8] Batman YuA, Volos LI Morphologic features of lung vessels at hypoxia due to primary pulmonary hypertension. Bulletin of urgent and recovery medicine. 2003; 8 (3): 402-405.
[9] Humbert M, Sitbon O, Yaici A, et al. Survival in incident and prevalent cohorts of patients with pulmonary arterial hypertension. European Respiratory Journal. 2010; 36 (3): 549-555.
[10] Senatorova A, Gonchar M, Boichenko A, Strashok A Primary pulmonary hypertension in children. Health of the child. 2007; 2 (5): 166-170.
[11] Guryanov VA, Tolmachev GN Primary (idiopathic) pulmonary hypertension (Ayerza-Arrillaga syndrome) and pregnancy – intensive care and management. Anesthesiology and reanimatology. 2014; 59 (6): 56-60.
[12] Sudakova NM, Gaplevskaya VF, Grevtseva NI, Trunova RB Ayers syndrome in child of the first year of life. Pediatrics. 2006; 6: 122-124.
[13] Porodenko NV, Skibitskiy VV, Zapevina VV The diagnosis and treatment of pulmonary hypertension: a modern view on the problem. Kuban Research Medical Herald. 2014; 3 (145): 140-144.
[14] Garkina SV, Adonina EV, Duplyakov DV, et al. Patient with primary pulmonary hypertension – who is he and how to help him? Clinician. 2011; 3: 103-105.
[15] Ataya A, Cope J, Hassan A A review of targeted pulmonary arterial hypertension – specific pharmacotherapy. J. Clin. Med. 2016; 5, 114: doi: 10.3390/jcm5120114.
[16] Rich JD, Rich S Clinical diagnosis of pulmonary hypertension. Circulation. 2014; 130: 1820-1830.
Cite This Article
  • APA Style

    Iryna Viktorivna Sorokina, Igor Volodymyrovych Kuznetsov, Iryna Vasylivna Borzenkova, Yuliia Igorivna Maslova, Mykhailo Sergiyovych Myroshnychenko, et al. (2017). Clinical and Morphological Features of Primary Pulmonary Hypertension: The Analysis of Two Cases from Practice. American Journal of Internal Medicine, 5(6), 112-116. https://doi.org/10.11648/j.ajim.20170506.11

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    ACS Style

    Iryna Viktorivna Sorokina; Igor Volodymyrovych Kuznetsov; Iryna Vasylivna Borzenkova; Yuliia Igorivna Maslova; Mykhailo Sergiyovych Myroshnychenko, et al. Clinical and Morphological Features of Primary Pulmonary Hypertension: The Analysis of Two Cases from Practice. Am. J. Intern. Med. 2017, 5(6), 112-116. doi: 10.11648/j.ajim.20170506.11

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    AMA Style

    Iryna Viktorivna Sorokina, Igor Volodymyrovych Kuznetsov, Iryna Vasylivna Borzenkova, Yuliia Igorivna Maslova, Mykhailo Sergiyovych Myroshnychenko, et al. Clinical and Morphological Features of Primary Pulmonary Hypertension: The Analysis of Two Cases from Practice. Am J Intern Med. 2017;5(6):112-116. doi: 10.11648/j.ajim.20170506.11

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  • @article{10.11648/j.ajim.20170506.11,
      author = {Iryna Viktorivna Sorokina and Igor Volodymyrovych Kuznetsov and Iryna Vasylivna Borzenkova and Yuliia Igorivna Maslova and Mykhailo Sergiyovych Myroshnychenko and Galyna Mykolayivna Saldan and Vitaliy Leonidovych Levinskiy and Olexiy Oleksandrovych Lyubchenko},
      title = {Clinical and Morphological Features of Primary Pulmonary Hypertension: The Analysis of Two Cases from Practice},
      journal = {American Journal of Internal Medicine},
      volume = {5},
      number = {6},
      pages = {112-116},
      doi = {10.11648/j.ajim.20170506.11},
      url = {https://doi.org/10.11648/j.ajim.20170506.11},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajim.20170506.11},
      abstract = {Primary pulmonary hypertension is a rare disease of unknown etiology, which is diagnosed in cases when examination of the patient with high blood pressure in the pulmonary artery does not allow determining its causes. The authors of this article analyze the literature data about primary pulmonary hypertension and report two cases from practice of this pathology. In one case of autopsy of 32-year-old woman primary pulmonary hypertension has been established during the investigation of autopsy material and in another case of autopsy of 52-year-old man this disease has been diagnosed during life. The description of the current state of the problem of primary pulmonary hypertension will be interesting to doctors of any specialization and will also allow to improve of physicians knowledge about this pathology.},
     year = {2017}
    }
    

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  • TY  - JOUR
    T1  - Clinical and Morphological Features of Primary Pulmonary Hypertension: The Analysis of Two Cases from Practice
    AU  - Iryna Viktorivna Sorokina
    AU  - Igor Volodymyrovych Kuznetsov
    AU  - Iryna Vasylivna Borzenkova
    AU  - Yuliia Igorivna Maslova
    AU  - Mykhailo Sergiyovych Myroshnychenko
    AU  - Galyna Mykolayivna Saldan
    AU  - Vitaliy Leonidovych Levinskiy
    AU  - Olexiy Oleksandrovych Lyubchenko
    Y1  - 2017/10/26
    PY  - 2017
    N1  - https://doi.org/10.11648/j.ajim.20170506.11
    DO  - 10.11648/j.ajim.20170506.11
    T2  - American Journal of Internal Medicine
    JF  - American Journal of Internal Medicine
    JO  - American Journal of Internal Medicine
    SP  - 112
    EP  - 116
    PB  - Science Publishing Group
    SN  - 2330-4324
    UR  - https://doi.org/10.11648/j.ajim.20170506.11
    AB  - Primary pulmonary hypertension is a rare disease of unknown etiology, which is diagnosed in cases when examination of the patient with high blood pressure in the pulmonary artery does not allow determining its causes. The authors of this article analyze the literature data about primary pulmonary hypertension and report two cases from practice of this pathology. In one case of autopsy of 32-year-old woman primary pulmonary hypertension has been established during the investigation of autopsy material and in another case of autopsy of 52-year-old man this disease has been diagnosed during life. The description of the current state of the problem of primary pulmonary hypertension will be interesting to doctors of any specialization and will also allow to improve of physicians knowledge about this pathology.
    VL  - 5
    IS  - 6
    ER  - 

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Author Information
  • Department of Pathological Anatomy, Kharkiv National Medical University, Kharkiv, Ukraine

  • Department of Cardiology, The Public Health Care Institution ?The Regional Clinical Hospital – The Center of Emergency Medical Care and Disaster Medicine?, Kharkiv, Ukraine

  • Department of Pathological Anatomy, The Public Health Care Institution ?The Regional Clinical Hospital – The Center of Emergency Medical Care and Disaster Medicine?, Kharkiv, Ukraine

  • Department of Pathological Anatomy, Kharkiv National Medical University, Kharkiv, Ukraine

  • Department of Pathological Anatomy, Kharkiv National Medical University, Kharkiv, Ukraine

  • The Public Health Care Institution ?The Center of Emergency Medical Care and Disaster Medicine?, Kharkiv, Ukraine

  • Department of Pathological Anatomy, The Public Health Care Institution ?The Regional Clinical Hospital – The Center of Emergency Medical Care and Disaster Medicine?, Kharkiv, Ukraine

  • Department of Pathological Anatomy, Kharkiv National Medical University, Kharkiv, Ukraine

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