Twenty four male rats weighing between 120-130g were randomly assigned into four groups. Group A was fed normal diet; Group B, C and D were fed hypercholesterolemic diet (i.e. 20% fat + 1% cholesterol) for two weeks to establish hypercholesterolemia. Thereafter, Group B were maintained on hyper diet, while C and D were fed 5% and 10% Sesamum indicum seed oil supplemented diet for four weeks. The liver and kidney were removed, dried and powdered. The concentrations of iron, zinc, cobalt, manganese, calcium, potassium, magnesium, potassium and sodium were analyzed in both liver and kidney samples with the use of Atomic Absorption Spectrophotometry. Hypercholesterolemia reduced both the hepatic and renal concentrations of sodium, potassium, Phosphorus, magnesium and calcium but reduced the hepatic and not the renal concentrations of manganese and zinc. Supplementation with 5% but not 10% Sesamum indicum seed oil reversed the effects and restored the reduced ions concentrations. The hepatic and renal concentrations of Iron and Cobalt ions were not affected by hypercholesterolemia nor by supplementation with Sesamum indicum seed oil.
| Published in | American Journal of Life Sciences (Volume 2, Issue 5) |
| DOI | 10.11648/j.ajls.20140205.19 |
| Page(s) | 308-311 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2014. Published by Science Publishing Group |
Hypercholesterolemia, Sesamum Indicum, Liver, Kidney, Mineral Concentration
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APA Style
Ajayi Olubunmi Bolanle, Malachi Oluwaseyi Israel. (2014). Effect of Sesamum indicum L. Seed oil Supplementation on Hepatic and Renal Mineral Concentrations of Hypercholesterolemic Rats. American Journal of Life Sciences, 2(5), 308-311. https://doi.org/10.11648/j.ajls.20140205.19
ACS Style
Ajayi Olubunmi Bolanle; Malachi Oluwaseyi Israel. Effect of Sesamum indicum L. Seed oil Supplementation on Hepatic and Renal Mineral Concentrations of Hypercholesterolemic Rats. Am. J. Life Sci. 2014, 2(5), 308-311. doi: 10.11648/j.ajls.20140205.19
AMA Style
Ajayi Olubunmi Bolanle, Malachi Oluwaseyi Israel. Effect of Sesamum indicum L. Seed oil Supplementation on Hepatic and Renal Mineral Concentrations of Hypercholesterolemic Rats. Am J Life Sci. 2014;2(5):308-311. doi: 10.11648/j.ajls.20140205.19
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Download@article{10.11648/j.ajls.20140205.19,
author = {Ajayi Olubunmi Bolanle and Malachi Oluwaseyi Israel},
title = {Effect of Sesamum indicum L. Seed oil Supplementation on Hepatic and Renal Mineral Concentrations of Hypercholesterolemic Rats},
journal = {American Journal of Life Sciences},
volume = {2},
number = {5},
pages = {308-311},
doi = {10.11648/j.ajls.20140205.19},
url = {https://doi.org/10.11648/j.ajls.20140205.19},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajls.20140205.19},
abstract = {Twenty four male rats weighing between 120-130g were randomly assigned into four groups. Group A was fed normal diet; Group B, C and D were fed hypercholesterolemic diet (i.e. 20% fat + 1% cholesterol) for two weeks to establish hypercholesterolemia. Thereafter, Group B were maintained on hyper diet, while C and D were fed 5% and 10% Sesamum indicum seed oil supplemented diet for four weeks. The liver and kidney were removed, dried and powdered. The concentrations of iron, zinc, cobalt, manganese, calcium, potassium, magnesium, potassium and sodium were analyzed in both liver and kidney samples with the use of Atomic Absorption Spectrophotometry. Hypercholesterolemia reduced both the hepatic and renal concentrations of sodium, potassium, Phosphorus, magnesium and calcium but reduced the hepatic and not the renal concentrations of manganese and zinc. Supplementation with 5% but not 10% Sesamum indicum seed oil reversed the effects and restored the reduced ions concentrations. The hepatic and renal concentrations of Iron and Cobalt ions were not affected by hypercholesterolemia nor by supplementation with Sesamum indicum seed oil.},
year = {2014}
}
TY - JOUR T1 - Effect of Sesamum indicum L. Seed oil Supplementation on Hepatic and Renal Mineral Concentrations of Hypercholesterolemic Rats AU - Ajayi Olubunmi Bolanle AU - Malachi Oluwaseyi Israel Y1 - 2014/10/30 PY - 2014 N1 - https://doi.org/10.11648/j.ajls.20140205.19 DO - 10.11648/j.ajls.20140205.19 T2 - American Journal of Life Sciences JF - American Journal of Life Sciences JO - American Journal of Life Sciences SP - 308 EP - 311 PB - Science Publishing Group SN - 2328-5737 UR - https://doi.org/10.11648/j.ajls.20140205.19 AB - Twenty four male rats weighing between 120-130g were randomly assigned into four groups. Group A was fed normal diet; Group B, C and D were fed hypercholesterolemic diet (i.e. 20% fat + 1% cholesterol) for two weeks to establish hypercholesterolemia. Thereafter, Group B were maintained on hyper diet, while C and D were fed 5% and 10% Sesamum indicum seed oil supplemented diet for four weeks. The liver and kidney were removed, dried and powdered. The concentrations of iron, zinc, cobalt, manganese, calcium, potassium, magnesium, potassium and sodium were analyzed in both liver and kidney samples with the use of Atomic Absorption Spectrophotometry. Hypercholesterolemia reduced both the hepatic and renal concentrations of sodium, potassium, Phosphorus, magnesium and calcium but reduced the hepatic and not the renal concentrations of manganese and zinc. Supplementation with 5% but not 10% Sesamum indicum seed oil reversed the effects and restored the reduced ions concentrations. The hepatic and renal concentrations of Iron and Cobalt ions were not affected by hypercholesterolemia nor by supplementation with Sesamum indicum seed oil. VL - 2 IS - 5 ER -
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