Therapeutic Efficiency of spirulina against Lead Acetate Toxicity on the Fresh Water Fish Labeo rohita

Manjunatha Bangeppagari; Jaffer Mohiddin Gooty; Juan Ortiz Tirado; Selvanayagam Mariadoss; Selvaraj Thangaswamy; Naga Raju Maddela; Darwin Rueda Ortiz

doi:doi:10.11648/j.ajls.20140206.19

Therapeutic Efficiency of spirulina against Lead Acetate Toxicity on the Fresh Water Fish Labeo rohita

Manjunatha Bangeppagari, Jaffer Mohiddin Gooty, Juan Ortiz Tirado, Selvanayagam Mariadoss, Selvaraj Thangaswamy, Naga Raju Maddela, Darwin Rueda Ortiz

Published in American Journal of Life Sciences (Volume 2, Issue 6)

Received: 13 December 2014 Accepted: 27 December 2014 Published: 4 January 2015

Views: Downloads:

Download PDF

Share This Article

Twitter
Linked In
Facebook

Abstract

The release of heavy metals in to the aquatic environment causes water pollution problems because of their toxicity, persistence and bioaccumulation. Lead has no known role to play in the human body that is physiologically relevant, and its harmful effects are myriad. Lead from the atmosphere and soil ends up in water bodies thus affecting the aquatic organisms. This situation has thus prompted numerous investigators to study on the effects of this heavy metal on the biological functions of aquatic organisms, particularly on the antioxidant enzyme activity in fish. In the present investigation the effect of lead acetate (heavy metal) on antioxidant enzyme activity was evaluated in the fresh water fish Labeo rohita. The experimental fish were treated with sub lethal concentration of lead acetate (0.015 mg/ L) for 120 hrs. Spirulina was used as supplementary feed during the experimental period. We observed various lead induced lipid peroxidation (LPO), antioxidant enzyme (SOD and CAT) changes and Spirulina supplementary feed therapeutic efficiency was observed in the gill and liver tissues of the fish. All the experimental data are statistically significant at p<0.05% level. The present study was under taken the toxic effect of lead acetate on Labeo rohita fish and chelating property of Spirulina.

Published in	American Journal of Life Sciences (Volume 2, Issue 6)
DOI	10.11648/j.ajls.20140206.19
Page(s)	389-394
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2015. Published by Science Publishing Group

Keywords

Antioxidant Enzymes, LPO, SOD, CAT, Labeo rohita, Lead Acetate, Spirulina

References

[1]	G.B. Mac Farlane and Burchettt, “Cellular distribution of Cu, Pb, and Zn in the Grey Mangrove Avicemniamarina (Forsk.),” Vierh Aquatic Botanica, vol. 68, pp: 45-59, 2000.
[2]	J.O. Duruibe, M.O.C. Ogwuegbu and J.N. Egwurugwu, “Heavy metal pollution and human biotoxic effects”, International Journal of Physical Sciences, vol. 2, pp: 112-118, 2007.
[3]	S. Khare and S. Singh, “Histopathological lessons induced by copper sulphate and lead nitrate in the gills of fresh water fish Nandus”, J. Ecotoxicol. Environ. Monit., vol. 12, pp: 105−111, 2002.
[4]	T.T. Gbem, J.K. Balogun, F.A. Lawaland and P.A. Annune, “Trace metal accumulation in Clariasgariepinus Teugules exposed to sublethal levels of tannery effluent”, Sci. Total Environ., vol. 271, pp: 1−9, 2001.
[5]	J.D. Woodling, S.F. Brinkman and B.J. Horn, “Nonuniform accumulation of cadmium and copper in kidney’s of wild Brown trout Salmotrutta populations”, Arch. Environ. Contam. Toxicol., vol. 40, pp: 318−385, 2001.
[6]	L. Coetzee, “Bioaccumulation of metals in selected fish species and the effects of pH on aluminum toxicity in a cichlid O. mossambicus”, 1st Edn, Randse Afrikanase Universitets, South Africa, 1998.
[7]	P. Guity, M.J. Mccabe, D.K. Pitts, R.P. Santini and J.G. Pounds, “Protein kinase C does not mediate the inhibitory action oflead onvitamin D3-dependent production of osteocalcin in osteoblastic bone cells”, Toxicology and Applied Pharmacology, vol. 178, pp: 109-116, 2002.
[8]	A.M. Saleh, C. Vijayasarathy, L. Masoud, L. Kumar, A. Shahin and A. Kambal, “Paraoxon induces apoptosis in EL4cells via activation of mitochondrial pathways”, Toxicology and Applied Pharmacology, vol. 90, pp: 47-57, 2003.
[9]	R. Van der Oost, J. Beyer and N.P.E. Vermeulen, “Fish bioaccumulation and biomarkers in environmental risk assessment:A review”, Environmental Toxicology and Pharmacology, vol. 13, pp: 57-149, 2003.
[10]	G.F. Nordberg, B.A. Fowler, M. Nordberg and L. Friberg, “Handbook on the Toxicology of Metals”, (3rd eds.), Academicpress, Amesterdam, ISBN-10: 0123694132, pp: 1024, 2007.
[11]	Y. M. Mobarak, “Review of the developmental toxicity and teratogenicity of three environmental contaminants(cadmium, lead and mercury)”, Catrina, vol. 3, pp: 31-43, 2008.
[12]	S.K. Park, J. Schwartz, M. Weisskopf, D. Sparrow and P.S. Vokonas, Low-level lead exposure, metabolic syndrome andheart ratevariability: The VA normative aging study”, Environ Health Perspect, vol. 114, pp: 1718-1724, 2006.
[13]	A.A. Berrahal, A. Nehdi, N. Hajjaji, N. Gharbi, and S. El-Fazaa, “Antioxidant enzymes activities and bilirubin levelinadult rat treated with lead”, C R Biol., vol. 330, pp: 581-588, 2007.
[14]	M.M. Reglero and M.A. Taggart, “Monsalve-Gonzalez L, Mateo R, Heavy metal exposure in large game from a leadmining area:effects on oxidative stress and fatty acid composition in liver”, Environ Pollut, vol. 157, pp: 1388-1395, 2009.
[15]	G.M. Abdallah, S.M. El-Sayed and O.M. Abo-Salem, “Effect of lead toxicity on co-enzyme Q levels in rat tissues”, Food Chem Toxicol, vol. 48, pp: 1753 – 1756, 2010.
[16]	Y.M.S. Mobarak and M.M. Sharaf, “Lead acetate induced histopathological changes in the gills and digestive system ofsilver sailfin (Poecilialatipinna)”, Int J Zool Res, vol. 7, pp:1-18, 2011.
[17]	E. Pinto, T.C.S. Sigaud-Kutner, M.A.S. Leitao, O.K. Okamoto, D. Morse and P. Colepicolo, “Heavy metal-inducedoxidative stress in algae”, Journal of Phycology, vol. 39, pp: 1008-1018, 2003.
[18]	B.N. Tripathi, S.K. Mehta, A. Amar and J.P. Gaur, “Oxidative stress in Scenedesmussp. during short and long- termexposure to Cu2+and Zn2”, Chemosphere, vol. 62, pp: 538- 544, 2006.
[19]	M.J. Bashir and NEM. Zuhair, “Histochemical demonstration of the alterations in the renal dehydrogenases activitiesinduced by leadin wistar albino rats (Rattusnorvegicus)”, Journal of Health Science, vol. 48(2), pp: 106 – 117, 2008.
[20]	J. Villeda - Hernandez, R. Barroso – Moguel, M. Mendez – Armenta, C. Nava –Ruiz, R. Huerta – Romero and C. Rios, “Enhancedbrain regional lipid peroxidation in developing rats exposed to low level lead acetate”, Brain Res Bull., vol. 55, pp: 247 – 251, 2001.
[21]	C.D. Upasani, A. Khera and R. Balaraman, “Effect of lead with Vitamins E, C or Spirulinaon malondialdehyde: conjugated dienes and hydroperoxides in rats.”, Ind. J. Exp. Biol., vol. 39(1), pp: 70 – 74, 2001.
[22]	R.P. Shaikh Afsar, R.S. Mali, Magar and K.V. Dube, “Recovery of Proteins from Lead Exposed Freshwater Fish Anabastestudineus”, International Journal of Research in Pharmaceutical and Biomedical Sciences, vol. 3(4), pp: 12 – 20, 2012.
[23]	A. Belay, T. Kato and Y. Ota, “Spirulina(Anthrospira); potential application as an animal feed supplement”, J. Appl. Phycol., vol. 8, pp: 303 – 311, 1996.
[24]	M. Rasool and E.P. Sabina, “Anti-inflammatory effect of Spirulina fusiformison adjuvant-induced arthritis in mice”, Biol. Pharm. Bull., vol. 29, pp: 2483 – 2487, 2006.
[25]	C.V. Seshadri, Umesh and R. Manoharan, “Beta carotene studies in Spirulina”, Bioresour Technol, vol. 38, pp: 111–113, 1991.
[26]	L.C. Wu, J.A. HO, M.C. Shieh and I.W. Lu, “Antioxidant and antiproliferative activities of Spirulina and chlorella water extracts. J.Agric Food Chem, vol. 53, pp: 4207 – 4212, 2005.
[27]	J.C. Dillon, A.P. Phuc and J.P. Dubacq, “Nutritional value of the algae Spirulina”, World Rev. Nutr. Diet, vol. 77, pp: 32-46, 1995.
[28]	R.L. Mendes, B.P. Norbe, M.T. Cardoso, A. Pereria, A.F. Palavra, M.S. Su Mirenda, R.G. Cintra, S.B.M. Barros and J. Mancini-Filho, “Antioxidant activity of the microalgae Spirulina maxima”, Braz. J. Med. Res., vol. 31(8), pp: 1075-1079, 1998.
[29]	M. Khan, J.C. Shoba, I.K. Mohan, M.U. Naidu, C. Sundaram, S. Singh, P. Kuppusamy and B.K. Kutala, “Effect of Spirulina against doxorubicin reduced cardio toxicity”, Phytother. Res., vol. 19(12), pp: 1030- 1037, 2005.
[30]	H.K. Lu, V. Hsieh, J.J. Hsu, Y.K. Yang and H.N. Chou, “Preventive effects of Spirulinaplatensison skeletal muscledamage under exercise-induced oxidative stress”, Eur. J. Appl. Physiol., vol. 98(2), pp: 220-226, 2006.
[31]	W.G. Niehaus and B. Samuelson, “Formation of malondialdehyde from phospholipid arachidonate during microsomallipidperoxidation”, Eur. J. Biochem., vol. 6, pp: 126 – 130, 1968.
[32]	P. Kakkar, B. Das and P.N. Viswanath, “A modified spectrophotometric assay of superoxide dismutase. Indian J.Biochem. Biophys., vol. 21, pp: 130, 1984.
[33]	K.A. Sinha, “Colorimetric assay of catalase. Anal.biochem., vol. 47, pp: 3889 – 3894, 1972.
[34]	I. Ahmad, T. Hamid, M. Fatima, H.S. Chand, S.K. Jain, M. Athar and S. Raisudeen, “Induction of hepaticantioxidants infreshwater catfish (Channapunctatus) is a biomarker of paper mill effluent exposure”, Biochem. Biophys. Acta., vol. 15, pp: 37- 48, 2000.
[35]	E. Pinto, T.C.S. Sigaud-Kutner, M.A.S. Leitao, O.K. Okamoto, D. Morse and P. Colepicolo, “Heavy metal-inducedoxidative stress in algae”, Journal of Phycology, vol. 39, pp: 1008-1018, 2003.
[36]	A.A.R. Radi and B. Matkovics, “Effects of metal ions on the antioxidant enzyme activities, protein contents and lipidperoxidation ofcarp tissues”, Comparative Biochemistry and Physiology, vol. 90C, pp: 69–72, 1988.
[37]	C. Dautremepuits, S. Paris-Palacios, S. Betoulle and G. Vernet, “Modulation in hepatic and head kidney parametersofcarp (CyprinuscarpioL.) induced by copper and chitosan”, Comparative Biochemistry and Physiology, vol. 137, pp: 325–333, 2004.
[38]	E. Baysoy, G. Atli, C.O. Gürler, Z. Dogan, A. AEroglu, K. Kocalar and M. Canli, “The effects of increased freshwatersalinity in thebiodisponibility of metals (Cr, Pb) and effects on antioxidant systems of Oreochromis niloticus”, Ecotoxicology and Environmental Safety, vol. 84, pp: 249–253, 2012.
[39]	N. Nagalakshmi and M.N.V. Prasad, “Copper-induced oxidative stres in Scenedesmusbijugatus: protective role of free radical scavengers”, Bulletin of Environmental Contamination and Toxicology, vol. 61, pp: 623–628, 1998.
[40]	D. Dewez, L. Geoffroy, G. Vernet and R. Popovic, “Determination of photosynthetic and enzymatic biomarkerssensitivity used toevaluate toxic effects of copper and fludioxonilin alga Scenedesmusobliquus”, Aquatic Toxicology, vol. 74, pp: 150–159, 2005.
[41]	N. Ercal, H. Gurer-Orhan and N. Aykin-Burns, “Toxic metals and oxidative stress part I: mechanismsinvolved ininduced oxidative damage”, Current Topics in Medical Chemistry, vol. 1, pp: 529–539, 2001.
[42]	R.M. Martinez-Alvares, A.E. Morales and A. Sanz, Antioxidant defenses in fish: Biotic and abiotic factors. Reviews in Fish Biology and Fisheries, vol. 15, pp: 75-88, 2005.
[43]	S.C. Gamble, P.S. Goldfarb, C. Porte and D.R. Livingston, “Glutathione peroxide and other antioxidant enzyme functionin marine invertebrates (Mytilusenpectenmammimus, Carcinus means and Asteriasrubens)”, Mar. Environm. Res., vol. 191-195, 1995.
[44]	C.D. Upasani and R. Balaraman, “Protective effect of Spirulinaon lead induced deleterious changes in the lipidperoxidation andendogenous antioxidants in rats”, Phytother. Res., vol. 17, pp: 330 – 334, 2003.
[45]	S.J. Flora, M. Panda and A. Mehta, “Beneficial effect of combined administration of some naturally occurringantioxidants (vitamins) and thiolchelators in the treatment at chronic lead intoxication”, Chem. Biol. Interact., vol. 145, pp: 267 – 280, 2003.
[46]	K. Hemalatha, K. Pugazhendy, K. Jayachandran, C. Jayanthi and M. Meenambal, “Studies on the protective efficacy of Spirulina against lead acetate induced hepatotoxicity in Rattusnorvegicus”, International Journal of Chemical and Analytical Science, vol. 3(8), pp: 1509 – 1512, 2012.
[47]	M.S. Balasubashini, R. Rukkumani, P. Viswanathan and V.P. Menon, “Ferulic acid alleviates lipid peroxidation indiabetic rats”, Phytother. Res., vol. 18, pp: 310 – 314, 2004.
[48]	R.A. Kohen and Nyska, “Oxidation of biological systems: oxidative phenomena, antioxidants, redox reactions, andmethods forquantifications”, Toxicol. Pathol., vol. 30, pp: 620-650, 2002.
[49]	E.O. Oruc and N. Uner, “Combined effects of 2,4D and azinphosmethyl antioxidant enzymes and lipid perxodation in liver of Oerochromis nilotes”, Comp. Biochem. Physicol., vol. 127, pp: 291-296, 2002.
[50]	R. Yilmaz, A. Atessahin, E. Sahna, I. Karahan and S. Ozer, “Protective effect of lycopene on adriamycininducedcardiotoxicity and nephrotoxicity”, Toxicology, vol. 218, pp: 164-171, 2006.
[51]	A.A. Mylroie, C. Umbles and J. Kyle, “Effects of dietary copper supplementation on erythrocyte superoxide dismutase activity, ceruloplasmin and related parameters in rats ingesting lead acetate. In: Hemphill, editor. Trace substances in environ health”, Columbia: University of Missouri Press, vol. 18, pp: 497 – 504, 1984.
[52]	V.K. Mazo, I.V. Gmoshinskii and I.S. Zilova, “Microalgae Spirulinain human nutrition”, Voprosy Pitoniia, vol. 73, pp: 45 –53, 2004.
[53]	A. Abdalla and El – Shebly, “The Role of Antioxidant (Vitamin E) in the Control of Lead (Pb) Pollution andEnhancement of Growth Within Nile Tilapia (Oreochromisniloticus)”, Intern J Appl Res Vet Med, vol. 7(3), pp: 20 –26, 2004.
[54]	A. Farhan, S. Kusum, Sapna Rani, A. Vinita and K. Shaista, “Effect of ascorbic acid against lead (Pb) toxicity”, International Journal of Pharmaceutical Sciences and Research, vol. 1(9), pp: 81 – 85, 2010.
[55]	H. Gerster, “Anticarcinogenic effect of common carotenoids”, Int. J. Vit. Nutr. Res., vol. 63, pp: 93 – 121, 1993.
[56]	C.V. Seshadri, B.V. Umesh and R. Manoharan, “Beta carotene studies in Spirulina”, Bioresour Technol, vol. 38, pp: 111–113, 1991.

Cite This Article

Plain Text BibTeX RIS

APA Style

Manjunatha Bangeppagari, Jaffer Mohiddin Gooty, Juan Ortiz Tirado, Selvanayagam Mariadoss, Selvaraj Thangaswamy, et al. (2015). Therapeutic Efficiency of spirulina against Lead Acetate Toxicity on the Fresh Water Fish Labeo rohita. American Journal of Life Sciences, 2(6), 389-394. https://doi.org/10.11648/j.ajls.20140206.19

Copy | Download

ACS Style

Manjunatha Bangeppagari; Jaffer Mohiddin Gooty; Juan Ortiz Tirado; Selvanayagam Mariadoss; Selvaraj Thangaswamy, et al. Therapeutic Efficiency of spirulina against Lead Acetate Toxicity on the Fresh Water Fish Labeo rohita. Am. J. Life Sci. 2015, 2(6), 389-394. doi: 10.11648/j.ajls.20140206.19

Copy | Download

AMA Style

Manjunatha Bangeppagari, Jaffer Mohiddin Gooty, Juan Ortiz Tirado, Selvanayagam Mariadoss, Selvaraj Thangaswamy, et al. Therapeutic Efficiency of spirulina against Lead Acetate Toxicity on the Fresh Water Fish Labeo rohita. Am J Life Sci. 2015;2(6):389-394. doi: 10.11648/j.ajls.20140206.19

Copy | Download

@article{10.11648/j.ajls.20140206.19,
  author = {Manjunatha Bangeppagari and Jaffer Mohiddin Gooty and Juan Ortiz Tirado and Selvanayagam Mariadoss and Selvaraj Thangaswamy and Naga Raju Maddela and Darwin Rueda Ortiz},
  title = {Therapeutic Efficiency of spirulina against Lead Acetate Toxicity on the Fresh Water Fish Labeo rohita},
  journal = {American Journal of Life Sciences},
  volume = {2},
  number = {6},
  pages = {389-394},
  doi = {10.11648/j.ajls.20140206.19},
  url = {https://doi.org/10.11648/j.ajls.20140206.19},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajls.20140206.19},
  abstract = {The release of heavy metals in to the aquatic environment causes water pollution problems because of their toxicity, persistence and bioaccumulation. Lead has no known role to play in the human body that is physiologically relevant, and its harmful effects are myriad. Lead from the atmosphere and soil ends up in water bodies thus affecting the aquatic organisms. This situation has thus prompted numerous investigators to study on the effects of this heavy metal on the biological functions of aquatic organisms, particularly on the antioxidant enzyme activity in fish. In the present investigation the effect of lead acetate (heavy metal) on antioxidant enzyme activity was evaluated in the fresh water fish Labeo rohita. The experimental fish were treated with sub lethal concentration of lead acetate (0.015 mg/ L) for 120 hrs. Spirulina was used as supplementary feed during the experimental period. We observed various lead induced lipid peroxidation (LPO), antioxidant enzyme (SOD and CAT) changes and Spirulina supplementary feed therapeutic efficiency was observed in the gill and liver tissues of the fish. All the experimental data are statistically significant at p<0.05% level. The present study was under taken the toxic effect of lead acetate on Labeo rohita fish and chelating property of Spirulina.},
 year = {2015}
}

Copy | Download

TY  - JOUR
T1  - Therapeutic Efficiency of spirulina against Lead Acetate Toxicity on the Fresh Water Fish Labeo rohita
AU  - Manjunatha Bangeppagari
AU  - Jaffer Mohiddin Gooty
AU  - Juan Ortiz Tirado
AU  - Selvanayagam Mariadoss
AU  - Selvaraj Thangaswamy
AU  - Naga Raju Maddela
AU  - Darwin Rueda Ortiz
Y1  - 2015/01/04
PY  - 2015
N1  - https://doi.org/10.11648/j.ajls.20140206.19
DO  - 10.11648/j.ajls.20140206.19
T2  - American Journal of Life Sciences
JF  - American Journal of Life Sciences
JO  - American Journal of Life Sciences
SP  - 389
EP  - 394
PB  - Science Publishing Group
SN  - 2328-5737
UR  - https://doi.org/10.11648/j.ajls.20140206.19
AB  - The release of heavy metals in to the aquatic environment causes water pollution problems because of their toxicity, persistence and bioaccumulation. Lead has no known role to play in the human body that is physiologically relevant, and its harmful effects are myriad. Lead from the atmosphere and soil ends up in water bodies thus affecting the aquatic organisms. This situation has thus prompted numerous investigators to study on the effects of this heavy metal on the biological functions of aquatic organisms, particularly on the antioxidant enzyme activity in fish. In the present investigation the effect of lead acetate (heavy metal) on antioxidant enzyme activity was evaluated in the fresh water fish Labeo rohita. The experimental fish were treated with sub lethal concentration of lead acetate (0.015 mg/ L) for 120 hrs. Spirulina was used as supplementary feed during the experimental period. We observed various lead induced lipid peroxidation (LPO), antioxidant enzyme (SOD and CAT) changes and Spirulina supplementary feed therapeutic efficiency was observed in the gill and liver tissues of the fish. All the experimental data are statistically significant at p<0.05% level. The present study was under taken the toxic effect of lead acetate on Labeo rohita fish and chelating property of Spirulina.
VL  - 2
IS  - 6
ER  -

Copy | Download

Author Information

Manjunatha Bangeppagari

Department of Zoology, Sri Krishnadevaraya University, Anantapur - 515003, Andhra Pradesh, India
Jaffer Mohiddin Gooty

Department of Life sciences, Universidad de las Fuerzas Armadas-ESPE, Sangolqui- POBOX: 171-5-231B, Quito, Ecuador, South America
Juan Ortiz Tirado

Department of Life sciences, Universidad de las Fuerzas Armadas-ESPE, Sangolqui- POBOX: 171-5-231B, Quito, Ecuador, South America
Selvanayagam Mariadoss

Department of Environmental Engineering, Universidad Estatal Amazonica, Puyo - 160150, Ecuador, South America
Selvaraj Thangaswamy

Centro de Biologia Cellular Y Molecular (CBCM), Universidad Technica Particular de Loja (UTPL), San Cayetano Alto s/n. Loja, Ecuador, C. P. 1101608, South America
Naga Raju Maddela

Department of Environmental Engineering, Universidad Estatal Amazonica, Puyo - 160150, Ecuador, South America
Darwin Rueda Ortiz

Department of Life sciences, Universidad de las Fuerzas Armadas-ESPE, Sangolqui- POBOX: 171-5-231B, Quito, Ecuador, South America

Download PDF

Sections

Plain Text BibTeX RIS

APA Style

Manjunatha Bangeppagari, Jaffer Mohiddin Gooty, Juan Ortiz Tirado, Selvanayagam Mariadoss, Selvaraj Thangaswamy, et al. (2015). Therapeutic Efficiency of spirulina against Lead Acetate Toxicity on the Fresh Water Fish Labeo rohita. American Journal of Life Sciences, 2(6), 389-394. https://doi.org/10.11648/j.ajls.20140206.19

Copy | Download

ACS Style

Manjunatha Bangeppagari; Jaffer Mohiddin Gooty; Juan Ortiz Tirado; Selvanayagam Mariadoss; Selvaraj Thangaswamy, et al. Therapeutic Efficiency of spirulina against Lead Acetate Toxicity on the Fresh Water Fish Labeo rohita. Am. J. Life Sci. 2015, 2(6), 389-394. doi: 10.11648/j.ajls.20140206.19

Copy | Download

AMA Style

Manjunatha Bangeppagari, Jaffer Mohiddin Gooty, Juan Ortiz Tirado, Selvanayagam Mariadoss, Selvaraj Thangaswamy, et al. Therapeutic Efficiency of spirulina against Lead Acetate Toxicity on the Fresh Water Fish Labeo rohita. Am J Life Sci. 2015;2(6):389-394. doi: 10.11648/j.ajls.20140206.19

Copy | Download

@article{10.11648/j.ajls.20140206.19,
  author = {Manjunatha Bangeppagari and Jaffer Mohiddin Gooty and Juan Ortiz Tirado and Selvanayagam Mariadoss and Selvaraj Thangaswamy and Naga Raju Maddela and Darwin Rueda Ortiz},
  title = {Therapeutic Efficiency of spirulina against Lead Acetate Toxicity on the Fresh Water Fish Labeo rohita},
  journal = {American Journal of Life Sciences},
  volume = {2},
  number = {6},
  pages = {389-394},
  doi = {10.11648/j.ajls.20140206.19},
  url = {https://doi.org/10.11648/j.ajls.20140206.19},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajls.20140206.19},
  abstract = {The release of heavy metals in to the aquatic environment causes water pollution problems because of their toxicity, persistence and bioaccumulation. Lead has no known role to play in the human body that is physiologically relevant, and its harmful effects are myriad. Lead from the atmosphere and soil ends up in water bodies thus affecting the aquatic organisms. This situation has thus prompted numerous investigators to study on the effects of this heavy metal on the biological functions of aquatic organisms, particularly on the antioxidant enzyme activity in fish. In the present investigation the effect of lead acetate (heavy metal) on antioxidant enzyme activity was evaluated in the fresh water fish Labeo rohita. The experimental fish were treated with sub lethal concentration of lead acetate (0.015 mg/ L) for 120 hrs. Spirulina was used as supplementary feed during the experimental period. We observed various lead induced lipid peroxidation (LPO), antioxidant enzyme (SOD and CAT) changes and Spirulina supplementary feed therapeutic efficiency was observed in the gill and liver tissues of the fish. All the experimental data are statistically significant at p<0.05% level. The present study was under taken the toxic effect of lead acetate on Labeo rohita fish and chelating property of Spirulina.},
 year = {2015}
}

Copy | Download

TY  - JOUR
T1  - Therapeutic Efficiency of spirulina against Lead Acetate Toxicity on the Fresh Water Fish Labeo rohita
AU  - Manjunatha Bangeppagari
AU  - Jaffer Mohiddin Gooty
AU  - Juan Ortiz Tirado
AU  - Selvanayagam Mariadoss
AU  - Selvaraj Thangaswamy
AU  - Naga Raju Maddela
AU  - Darwin Rueda Ortiz
Y1  - 2015/01/04
PY  - 2015
N1  - https://doi.org/10.11648/j.ajls.20140206.19
DO  - 10.11648/j.ajls.20140206.19
T2  - American Journal of Life Sciences
JF  - American Journal of Life Sciences
JO  - American Journal of Life Sciences
SP  - 389
EP  - 394
PB  - Science Publishing Group
SN  - 2328-5737
UR  - https://doi.org/10.11648/j.ajls.20140206.19
AB  - The release of heavy metals in to the aquatic environment causes water pollution problems because of their toxicity, persistence and bioaccumulation. Lead has no known role to play in the human body that is physiologically relevant, and its harmful effects are myriad. Lead from the atmosphere and soil ends up in water bodies thus affecting the aquatic organisms. This situation has thus prompted numerous investigators to study on the effects of this heavy metal on the biological functions of aquatic organisms, particularly on the antioxidant enzyme activity in fish. In the present investigation the effect of lead acetate (heavy metal) on antioxidant enzyme activity was evaluated in the fresh water fish Labeo rohita. The experimental fish were treated with sub lethal concentration of lead acetate (0.015 mg/ L) for 120 hrs. Spirulina was used as supplementary feed during the experimental period. We observed various lead induced lipid peroxidation (LPO), antioxidant enzyme (SOD and CAT) changes and Spirulina supplementary feed therapeutic efficiency was observed in the gill and liver tissues of the fish. All the experimental data are statistically significant at p<0.05% level. The present study was under taken the toxic effect of lead acetate on Labeo rohita fish and chelating property of Spirulina.
VL  - 2
IS  - 6
ER  -

Copy | Download