Introduction: According to 2011 Ethiopian demographic health survey, the national and Amhara Regional state administration adult HIV prevalence was 1.5 % and 2.2% respectively. The major causes of morbidity and mortality of PLWHA (people living with HIV/AIDS) patients are OIs (opportunistic infections) that would occur in up to 40% of PLWHA. OIs are repeatedly happening in HIV (Human Immunodeficiency Virus) infected patients though there is no prior local evidence on time gap of repetition. Therefore the current study is aimed to determine time gap between repeated re-happening OIs and its associated factors among PLWHA who are initiated ART (Anti-Retroviral Treatment). Method: Institution based retrospective cohort study was conducted among 364 systematically selected PLWHA commencing ART. Time-gap was estimated using Kaplan-meier survival and actuarial life table. Hazard rate was calculated using Cox proportional-hazard model. Result: during follow up OIs were re-diagnosed in about three quarter (76.9%) of participants. In each week the probability of getting the re-happened OI was 1.1 per 100 persons. The median duration of staying free of OI re-happening was 66 weeks. In multivariate analysis using logistic regression, educational status, marital status, Prophylaxisis exposure, ART and Prophylaxisis drug adherence, hemoglobin and CD4 level were significantly associated with time gap of relapse. Thus organizations working on HIV/AIDS should further work to enhance time gap of relapse.
| Published in | Clinical Medicine Research (Volume 4, Issue 1) |
| DOI | 10.11648/j.cmr.20150401.13 |
| Page(s) | 11-16 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2015. Published by Science Publishing Group |
HIV/AIDS, Re-Happening, ART, PLWHA, Ethiopia
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APA Style
Habtamu Mellie Bizuayehu. (2015). The Time Gap between Repeated Re-Happening Opportunistic Infections among People Living with HIV/AIDS Commencing Antiretroviral Treatment. Clinical Medicine Research, 4(1), 11-16. https://doi.org/10.11648/j.cmr.20150401.13
ACS Style
Habtamu Mellie Bizuayehu. The Time Gap between Repeated Re-Happening Opportunistic Infections among People Living with HIV/AIDS Commencing Antiretroviral Treatment. Clin. Med. Res. 2015, 4(1), 11-16. doi: 10.11648/j.cmr.20150401.13
AMA Style
Habtamu Mellie Bizuayehu. The Time Gap between Repeated Re-Happening Opportunistic Infections among People Living with HIV/AIDS Commencing Antiretroviral Treatment. Clin Med Res. 2015;4(1):11-16. doi: 10.11648/j.cmr.20150401.13
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Download@article{10.11648/j.cmr.20150401.13,
author = {Habtamu Mellie Bizuayehu},
title = {The Time Gap between Repeated Re-Happening Opportunistic Infections among People Living with HIV/AIDS Commencing Antiretroviral Treatment},
journal = {Clinical Medicine Research},
volume = {4},
number = {1},
pages = {11-16},
doi = {10.11648/j.cmr.20150401.13},
url = {https://doi.org/10.11648/j.cmr.20150401.13},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.cmr.20150401.13},
abstract = {Introduction: According to 2011 Ethiopian demographic health survey, the national and Amhara Regional state administration adult HIV prevalence was 1.5 % and 2.2% respectively. The major causes of morbidity and mortality of PLWHA (people living with HIV/AIDS) patients are OIs (opportunistic infections) that would occur in up to 40% of PLWHA. OIs are repeatedly happening in HIV (Human Immunodeficiency Virus) infected patients though there is no prior local evidence on time gap of repetition. Therefore the current study is aimed to determine time gap between repeated re-happening OIs and its associated factors among PLWHA who are initiated ART (Anti-Retroviral Treatment). Method: Institution based retrospective cohort study was conducted among 364 systematically selected PLWHA commencing ART. Time-gap was estimated using Kaplan-meier survival and actuarial life table. Hazard rate was calculated using Cox proportional-hazard model. Result: during follow up OIs were re-diagnosed in about three quarter (76.9%) of participants. In each week the probability of getting the re-happened OI was 1.1 per 100 persons. The median duration of staying free of OI re-happening was 66 weeks. In multivariate analysis using logistic regression, educational status, marital status, Prophylaxisis exposure, ART and Prophylaxisis drug adherence, hemoglobin and CD4 level were significantly associated with time gap of relapse. Thus organizations working on HIV/AIDS should further work to enhance time gap of relapse.},
year = {2015}
}
TY - JOUR T1 - The Time Gap between Repeated Re-Happening Opportunistic Infections among People Living with HIV/AIDS Commencing Antiretroviral Treatment AU - Habtamu Mellie Bizuayehu Y1 - 2015/02/02 PY - 2015 N1 - https://doi.org/10.11648/j.cmr.20150401.13 DO - 10.11648/j.cmr.20150401.13 T2 - Clinical Medicine Research JF - Clinical Medicine Research JO - Clinical Medicine Research SP - 11 EP - 16 PB - Science Publishing Group SN - 2326-9057 UR - https://doi.org/10.11648/j.cmr.20150401.13 AB - Introduction: According to 2011 Ethiopian demographic health survey, the national and Amhara Regional state administration adult HIV prevalence was 1.5 % and 2.2% respectively. The major causes of morbidity and mortality of PLWHA (people living with HIV/AIDS) patients are OIs (opportunistic infections) that would occur in up to 40% of PLWHA. OIs are repeatedly happening in HIV (Human Immunodeficiency Virus) infected patients though there is no prior local evidence on time gap of repetition. Therefore the current study is aimed to determine time gap between repeated re-happening OIs and its associated factors among PLWHA who are initiated ART (Anti-Retroviral Treatment). Method: Institution based retrospective cohort study was conducted among 364 systematically selected PLWHA commencing ART. Time-gap was estimated using Kaplan-meier survival and actuarial life table. Hazard rate was calculated using Cox proportional-hazard model. Result: during follow up OIs were re-diagnosed in about three quarter (76.9%) of participants. In each week the probability of getting the re-happened OI was 1.1 per 100 persons. The median duration of staying free of OI re-happening was 66 weeks. In multivariate analysis using logistic regression, educational status, marital status, Prophylaxisis exposure, ART and Prophylaxisis drug adherence, hemoglobin and CD4 level were significantly associated with time gap of relapse. Thus organizations working on HIV/AIDS should further work to enhance time gap of relapse. VL - 4 IS - 1 ER -
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