Therapeutic Itinerary of the Patients Followed for Myasthenia Gravis in Dakar

Kaba Yacouba; Mourabit Salaheddine; Atsa Kouda Daniel; Affognon Cadnelle Christelle; Bugeme Marcellin; Fall Maouly; Seck Lala Bouna; Ndiaye Moustapha; Diop Gallo Amadou

doi:doi:10.11648/j.cnn.20200401.14

Therapeutic Itinerary of the Patients Followed for Myasthenia Gravis in Dakar

Kaba Yacouba, Mourabit Salaheddine, Atsa Kouda Daniel, Affognon Cadnelle Christelle, Bugeme Marcellin, Fall Maouly, Seck Lala Bouna, Ndiaye Moustapha, Diop Gallo Amadou

Published in Clinical Neurology and Neuroscience (Volume 4, Issue 1)

Received: 19 June 2019 Accepted: 6 February 2020 Published: 14 February 2020

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Abstract

Introduction: Myasthenia gravis is an autoimmune disease caused by specific autoantibodies that induce dysfunction of neuromuscular transmission. The diagnostic procedure is similar regardless of the age of the subject. As in any disease, the management starts with the diagnosis, which is often unduly delayed. The purpose of our study was to evaluate the reasons for this delay. Methodology: This was a retrospective, transversal, and descriptive study on the files of myasthenic subjects followed over a period of four years (2014 to 2017) at the neuroscience clinic of the Univresity National Center of Fann and at the consultation of neurology of the Pikine National Hospital Center where a hetero-administered questionnaire was completed. Results: The study involved 18 myasthenic patients including 13 women and 5 men with a sex ratio of 2.6. The median age of the patients was 32 years [14 - 60 years]. The average time to patient diagnosis was 24 months. The patients had consulted on average four times before the diagnosis of myasthenia gravis. The referral hospital was the facility attended by 78% of patients and the ophthalmology service was the first service consulted by 13 patients, or 72%. The median age at onset of symptoms was 28 years. Ptosis was the first symptom in 56% of the cases. Conclusion: Myasthenia gravis is a disorder little known to the public and to practitioners. The ophthalmologist was the first remedy. It would be wise for any practitioner to know the main manifestations.

Published in	Clinical Neurology and Neuroscience (Volume 4, Issue 1)
DOI	10.11648/j.cnn.20200401.14
Page(s)	18-23
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2020. Published by Science Publishing Group

Keywords

Myasthenia Gravis, Therapeutic Itinerary, Dakar

References

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APA Style

Kaba Yacouba, Mourabit Salaheddine, Atsa Kouda Daniel, Affognon Cadnelle Christelle, Bugeme Marcellin, et al. (2020). Therapeutic Itinerary of the Patients Followed for Myasthenia Gravis in Dakar. Clinical Neurology and Neuroscience, 4(1), 18-23. https://doi.org/10.11648/j.cnn.20200401.14

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ACS Style

Kaba Yacouba; Mourabit Salaheddine; Atsa Kouda Daniel; Affognon Cadnelle Christelle; Bugeme Marcellin, et al. Therapeutic Itinerary of the Patients Followed for Myasthenia Gravis in Dakar. Clin. Neurol. Neurosci. 2020, 4(1), 18-23. doi: 10.11648/j.cnn.20200401.14

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AMA Style

Kaba Yacouba, Mourabit Salaheddine, Atsa Kouda Daniel, Affognon Cadnelle Christelle, Bugeme Marcellin, et al. Therapeutic Itinerary of the Patients Followed for Myasthenia Gravis in Dakar. Clin Neurol Neurosci. 2020;4(1):18-23. doi: 10.11648/j.cnn.20200401.14

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@article{10.11648/j.cnn.20200401.14,
  author = {Kaba Yacouba and Mourabit Salaheddine and Atsa Kouda Daniel and Affognon Cadnelle Christelle and Bugeme Marcellin and Fall Maouly and Seck Lala Bouna and Ndiaye Moustapha and Diop Gallo Amadou},
  title = {Therapeutic Itinerary of the Patients Followed for Myasthenia Gravis in Dakar},
  journal = {Clinical Neurology and Neuroscience},
  volume = {4},
  number = {1},
  pages = {18-23},
  doi = {10.11648/j.cnn.20200401.14},
  url = {https://doi.org/10.11648/j.cnn.20200401.14},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.cnn.20200401.14},
  abstract = {Introduction: Myasthenia gravis is an autoimmune disease caused by specific autoantibodies that induce dysfunction of neuromuscular transmission. The diagnostic procedure is similar regardless of the age of the subject. As in any disease, the management starts with the diagnosis, which is often unduly delayed. The purpose of our study was to evaluate the reasons for this delay. Methodology: This was a retrospective, transversal, and descriptive study on the files of myasthenic subjects followed over a period of four years (2014 to 2017) at the neuroscience clinic of the Univresity National Center of Fann and at the consultation of neurology of the Pikine National Hospital Center where a hetero-administered questionnaire was completed. Results: The study involved 18 myasthenic patients including 13 women and 5 men with a sex ratio of 2.6. The median age of the patients was 32 years [14 - 60 years]. The average time to patient diagnosis was 24 months. The patients had consulted on average four times before the diagnosis of myasthenia gravis. The referral hospital was the facility attended by 78% of patients and the ophthalmology service was the first service consulted by 13 patients, or 72%. The median age at onset of symptoms was 28 years. Ptosis was the first symptom in 56% of the cases. Conclusion: Myasthenia gravis is a disorder little known to the public and to practitioners. The ophthalmologist was the first remedy. It would be wise for any practitioner to know the main manifestations.},
 year = {2020}
}

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TY - JOUR
T1 - Therapeutic Itinerary of the Patients Followed for Myasthenia Gravis in Dakar
AU - Kaba Yacouba
AU - Mourabit Salaheddine
AU - Atsa Kouda Daniel
AU - Affognon Cadnelle Christelle
AU - Bugeme Marcellin
AU - Fall Maouly
AU - Seck Lala Bouna
AU - Ndiaye Moustapha
AU - Diop Gallo Amadou
Y1 - 2020/02/14
PY - 2020
N1 - https://doi.org/10.11648/j.cnn.20200401.14
DO - 10.11648/j.cnn.20200401.14
T2 - Clinical Neurology and Neuroscience
JF - Clinical Neurology and Neuroscience
JO - Clinical Neurology and Neuroscience
SP - 18
EP - 23
PB - Science Publishing Group
SN - 2578-8930
UR - https://doi.org/10.11648/j.cnn.20200401.14
AB - Introduction: Myasthenia gravis is an autoimmune disease caused by specific autoantibodies that induce dysfunction of neuromuscular transmission. The diagnostic procedure is similar regardless of the age of the subject. As in any disease, the management starts with the diagnosis, which is often unduly delayed. The purpose of our study was to evaluate the reasons for this delay. Methodology: This was a retrospective, transversal, and descriptive study on the files of myasthenic subjects followed over a period of four years (2014 to 2017) at the neuroscience clinic of the Univresity National Center of Fann and at the consultation of neurology of the Pikine National Hospital Center where a hetero-administered questionnaire was completed. Results: The study involved 18 myasthenic patients including 13 women and 5 men with a sex ratio of 2.6. The median age of the patients was 32 years [14 - 60 years]. The average time to patient diagnosis was 24 months. The patients had consulted on average four times before the diagnosis of myasthenia gravis. The referral hospital was the facility attended by 78% of patients and the ophthalmology service was the first service consulted by 13 patients, or 72%. The median age at onset of symptoms was 28 years. Ptosis was the first symptom in 56% of the cases. Conclusion: Myasthenia gravis is a disorder little known to the public and to practitioners. The ophthalmologist was the first remedy. It would be wise for any practitioner to know the main manifestations.
VL - 4
IS - 1
ER -

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Author Information

Kaba Yacouba

Neurology Department, Faculty of Medicine, Pharmacy and Dentistry of the Sheikh Anta Diop University of Dakar, Neurosciences Clinic I. P Ndiaye – Fann National University Hospital Center, Dakar-Senegal
Mourabit Salaheddine

Neurology Department, Faculty of Medicine, Pharmacy and Dentistry of the Sheikh Anta Diop University of Dakar, Neurosciences Clinic I. P Ndiaye – Fann National University Hospital Center, Dakar-Senegal
Atsa Kouda Daniel

Neurology Department, Faculty of Medicine, Pharmacy and Dentistry of the Sheikh Anta Diop University of Dakar, Neurosciences Clinic I. P Ndiaye – Fann National University Hospital Center, Dakar-Senegal
Affognon Cadnelle Christelle

Neurology Department, Faculty of Medicine, Pharmacy and Dentistry of the Sheikh Anta Diop University of Dakar, Neurosciences Clinic I. P Ndiaye – Fann National University Hospital Center, Dakar-Senegal
Bugeme Marcellin

Neurology Department, Faculty of Medicine, Pharmacy and Dentistry of the Sheikh Anta Diop University of Dakar, Neurosciences Clinic I. P Ndiaye – Fann National University Hospital Center, Dakar-Senegal
Fall Maouly

Neurology Department, Faculty of Medicine, Pharmacy and Dentistry of the Sheikh Anta Diop University of Dakar, Pikine National Hospital, Dakar-Senegal
Seck Lala Bouna

Neurology Department, Faculty of Medicine, Pharmacy and Dentistry of the Sheikh Anta Diop University of Dakar, Neurosciences Clinic I. P Ndiaye – Fann National University Hospital Center, Dakar-Senegal
Ndiaye Moustapha

Neurology Department, Faculty of Medicine, Pharmacy and Dentistry of the Sheikh Anta Diop University of Dakar, Neurosciences Clinic I. P Ndiaye – Fann National University Hospital Center, Dakar-Senegal
Diop Gallo Amadou

Neurology Department, Faculty of Medicine, Pharmacy and Dentistry of the Sheikh Anta Diop University of Dakar, Neurosciences Clinic I. P Ndiaye – Fann National University Hospital Center, Dakar-Senegal

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APA Style

Kaba Yacouba, Mourabit Salaheddine, Atsa Kouda Daniel, Affognon Cadnelle Christelle, Bugeme Marcellin, et al. (2020). Therapeutic Itinerary of the Patients Followed for Myasthenia Gravis in Dakar. Clinical Neurology and Neuroscience, 4(1), 18-23. https://doi.org/10.11648/j.cnn.20200401.14

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ACS Style

Kaba Yacouba; Mourabit Salaheddine; Atsa Kouda Daniel; Affognon Cadnelle Christelle; Bugeme Marcellin, et al. Therapeutic Itinerary of the Patients Followed for Myasthenia Gravis in Dakar. Clin. Neurol. Neurosci. 2020, 4(1), 18-23. doi: 10.11648/j.cnn.20200401.14

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AMA Style

Kaba Yacouba, Mourabit Salaheddine, Atsa Kouda Daniel, Affognon Cadnelle Christelle, Bugeme Marcellin, et al. Therapeutic Itinerary of the Patients Followed for Myasthenia Gravis in Dakar. Clin Neurol Neurosci. 2020;4(1):18-23. doi: 10.11648/j.cnn.20200401.14

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@article{10.11648/j.cnn.20200401.14,
  author = {Kaba Yacouba and Mourabit Salaheddine and Atsa Kouda Daniel and Affognon Cadnelle Christelle and Bugeme Marcellin and Fall Maouly and Seck Lala Bouna and Ndiaye Moustapha and Diop Gallo Amadou},
  title = {Therapeutic Itinerary of the Patients Followed for Myasthenia Gravis in Dakar},
  journal = {Clinical Neurology and Neuroscience},
  volume = {4},
  number = {1},
  pages = {18-23},
  doi = {10.11648/j.cnn.20200401.14},
  url = {https://doi.org/10.11648/j.cnn.20200401.14},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.cnn.20200401.14},
  abstract = {Introduction: Myasthenia gravis is an autoimmune disease caused by specific autoantibodies that induce dysfunction of neuromuscular transmission. The diagnostic procedure is similar regardless of the age of the subject. As in any disease, the management starts with the diagnosis, which is often unduly delayed. The purpose of our study was to evaluate the reasons for this delay. Methodology: This was a retrospective, transversal, and descriptive study on the files of myasthenic subjects followed over a period of four years (2014 to 2017) at the neuroscience clinic of the Univresity National Center of Fann and at the consultation of neurology of the Pikine National Hospital Center where a hetero-administered questionnaire was completed. Results: The study involved 18 myasthenic patients including 13 women and 5 men with a sex ratio of 2.6. The median age of the patients was 32 years [14 - 60 years]. The average time to patient diagnosis was 24 months. The patients had consulted on average four times before the diagnosis of myasthenia gravis. The referral hospital was the facility attended by 78% of patients and the ophthalmology service was the first service consulted by 13 patients, or 72%. The median age at onset of symptoms was 28 years. Ptosis was the first symptom in 56% of the cases. Conclusion: Myasthenia gravis is a disorder little known to the public and to practitioners. The ophthalmologist was the first remedy. It would be wise for any practitioner to know the main manifestations.},
 year = {2020}
}

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