Characteristics of Epilepsy in Children with Cerebral Palsy

Denis Fiolita; I Gusti Ngurah Made Suwarba; Dewi Sutriani Mahalini

doi:doi:10.11648/j.cnn.20200402.12

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Characteristics of Epilepsy in Children with Cerebral Palsy

Denis Fiolita, I Gusti Ngurah Made Suwarba, Dewi Sutriani Mahalini

Published in Clinical Neurology and Neuroscience (Volume 4, Issue 2)

Received: 10 May 2020 Accepted: 27 May 2020 Published: 4 June 2020

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Abstract

Cerebral palsy is a disorder of movement and posture due to disruption of the immature motoric cells in central nervous systems. It is characterized by various neurological abnormalities, one of them is epilepsy. Epilepsy is difficult to control, as it is able to aggravate motor disorders and disrupt cognitive function, ultimately worsening the long-term outcome. This research aims to determine the characteristics of epilepsy in children with cerebral palsy. A cross-sectional study was done based on medical records data Pediatric Outpatient Department and Medical Rehabilitation Installation Sanglah Hospital from January 2016 until June 2018. Eighty-four samples were included. Most of the samples were female (53.6%) with mean of age was 64 months and onset of epilepsy was 21 months. Regarding to nutritional status, most of them with undernutrition (44%). Based on birth history, 66.7% of them was born by spontaneous delivery, 34.5% with asphyxia and 82.1% were normal birth weight. Generalized seizure was the most common type of seizure (81%). Most types of cerebral palsy were spastic type (94%). History of seizures at <1 year of age was 63.1%. History of central nervous system infection was 15.5%. The most brain abnormalities was microcephaly (34.5%). Abnormal EEG results were about 91.7%, with family history of seizures was 1.2%. Frequency of polytherapy with anti-epileptic drugs was 69%. The most common type of cerebral palsy in this research was spastic type. Generalized seizure was the most common type of seizure in epilepsy children with cerebral palsy. Most of them have abnormal EEG results and need more than one anti-epileptic therapy.

Published in	Clinical Neurology and Neuroscience (Volume 4, Issue 2)
DOI	10.11648/j.cnn.20200402.12
Page(s)	29-32
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2020. Published by Science Publishing Group

Keywords

Cerebral palsy, Characteristic, Epilepsy

References

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[2]	Mwesige AK, Andrews C, Peterson F, Mangen FW, Eliasson AC, Forssberg H. Prevalence of Cerebral Palsy in Uganda: a population based study. The Lancet Global Health. Vol. 5, No. 2, 2017, pp. 1-7.
[3]	Bearden DR, Monokwane B, Khurana E, Baier J, Baranov E, Westmoreland K, dkk. Pediatric Cerebral Palsy in Botswana: etiology, outcomes and comorbidities. Pediatric Neurology. Vol. 59, 2016, pp. 1-16.
[4]	Reddy B, Ashok, Eluzai Z. A Study of Clinical Spectrum and Risk Factors of Cerebral Palsy in Children. IOSR Journal of Dental and Medicine Science. Vol. 17, No. 1, 2018, pp. 49-52.
[5]	Salam OA, Esmael A, El-Sherif M. Epilepsy among Cerebral Palsy Children: clinical predictors and frequency. International Neuropsychiatric Disease Journal. Vol. 6, No. 2, 2016, pp. 1-8.
[6]	Mangunatmadja, Handryastuti S, Soetomenggolo HAF, Soebadi A, Nurmalia LD. Epilepsi pada anak. in: Mangunatmadja I, Handryastuti S, Risan NA, editors. Buku edukasi dokter. 1^st edition. Jakarta. IDAI, 2016, pp. 1-66.
[7]	Suwarba IGNM. Insiden dan karakteristik klinis epilepsi pada anak. Sari Pediatri. Vo. 13, No. 2, 2011, pp. 123-8.
[8]	Bruck I, Antoniuk A, Spessato A, dkk. Epilepsy in Children with Cerebral Palsy. Arquivos de Neuro Psiquiatria. Vo. 59, No. 1, 2001, pp. 35-9.
[9]	Rempel G. The Importance of Good Nutrition in Children with Cerebral Palsy. Physical Medicine Rehabilitation Clinics of North America. Vol. 26, No. 1, 2015, pp. 39-56.
[10]	Aroujo LA, Silva LR. Antrhropometric Assessment of Patients with Cerebral Palsy: which curves are more appropriate?. Jornal de Pediatria. Vol. 89, No. 3, 2013, pp. 307-14.
[11]	Aydin K. A Multicenter Cross-sectional Study to Evaluate The Clinical Characteristic and Nutritional Status of Children with Cerebral Palsy. Clinical Nutrition ESPEN. Vol. 26, 2018, 27-34.
[12]	Rahmat D, Mangunatmadja I, Tridjaja B, Tambunan T, Suradi R. Prevalence and Risk Factors for Epilepsy in Children with Spastic Cerebral Palsy. Paediatrica Indonesiana. Vol. 50, No. 1, 2010, pp. 11-7.
[13]	Sellier E, Uldall P, Calado E, Sigurdardottir S, Torrioli MG, Platt MJ, dkk. Epilepsy and Cerebral Palsy: characteristics and trends in children born in 1976-1998. European Journal of Pediatric Neurology. Vol. 16, No. 1, 2012, pp. 48-55.
[14]	Wibowo AR, Saputra DR. Prevalens dan Profil Klinis pada Anak Palsi Serebral Spastik dengan Epilepsi. Sari Pediatri. Vol. 14, No. 1, 2012, pp. 1-7.
[15]	Gururaj AK, Sztriha L, Bner A, Eapen V. Epilepsy in Children with Cerebral Palsy. Seizure. Vol. 12, No. 2, 2003, pp. 110-4.

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APA Style

Denis Fiolita, I Gusti Ngurah Made Suwarba, Dewi Sutriani Mahalini. (2020). Characteristics of Epilepsy in Children with Cerebral Palsy. Clinical Neurology and Neuroscience, 4(2), 29-32. https://doi.org/10.11648/j.cnn.20200402.12

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ACS Style

Denis Fiolita; I Gusti Ngurah Made Suwarba; Dewi Sutriani Mahalini. Characteristics of Epilepsy in Children with Cerebral Palsy. Clin. Neurol. Neurosci. 2020, 4(2), 29-32. doi: 10.11648/j.cnn.20200402.12

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AMA Style

Denis Fiolita, I Gusti Ngurah Made Suwarba, Dewi Sutriani Mahalini. Characteristics of Epilepsy in Children with Cerebral Palsy. Clin Neurol Neurosci. 2020;4(2):29-32. doi: 10.11648/j.cnn.20200402.12

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@article{10.11648/j.cnn.20200402.12,
  author = {Denis Fiolita and I Gusti Ngurah Made Suwarba and Dewi Sutriani Mahalini},
  title = {Characteristics of Epilepsy in Children with Cerebral Palsy},
  journal = {Clinical Neurology and Neuroscience},
  volume = {4},
  number = {2},
  pages = {29-32},
  doi = {10.11648/j.cnn.20200402.12},
  url = {https://doi.org/10.11648/j.cnn.20200402.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.cnn.20200402.12},
  abstract = {Cerebral palsy is a disorder of movement and posture due to disruption of the immature motoric cells in central nervous systems. It is characterized by various neurological abnormalities, one of them is epilepsy. Epilepsy is difficult to control, as it is able to aggravate motor disorders and disrupt cognitive function, ultimately worsening the long-term outcome. This research aims to determine the characteristics of epilepsy in children with cerebral palsy. A cross-sectional study was done based on medical records data Pediatric Outpatient Department and Medical Rehabilitation Installation Sanglah Hospital from January 2016 until June 2018. Eighty-four samples were included. Most of the samples were female (53.6%) with mean of age was 64 months and onset of epilepsy was 21 months. Regarding to nutritional status, most of them with undernutrition (44%). Based on birth history, 66.7% of them was born by spontaneous delivery, 34.5% with asphyxia and 82.1% were normal birth weight. Generalized seizure was the most common type of seizure (81%). Most types of cerebral palsy were spastic type (94%). History of seizures at <1 year of age was 63.1%. History of central nervous system infection was 15.5%. The most brain abnormalities was microcephaly (34.5%). Abnormal EEG results were about 91.7%, with family history of seizures was 1.2%. Frequency of polytherapy with anti-epileptic drugs was 69%. The most common type of cerebral palsy in this research was spastic type. Generalized seizure was the most common type of seizure in epilepsy children with cerebral palsy. Most of them have abnormal EEG results and need more than one anti-epileptic therapy.},
 year = {2020}
}

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TY - JOUR
T1 - Characteristics of Epilepsy in Children with Cerebral Palsy
AU - Denis Fiolita
AU - I Gusti Ngurah Made Suwarba
AU - Dewi Sutriani Mahalini
Y1 - 2020/06/04
PY - 2020
N1 - https://doi.org/10.11648/j.cnn.20200402.12
DO - 10.11648/j.cnn.20200402.12
T2 - Clinical Neurology and Neuroscience
JF - Clinical Neurology and Neuroscience
JO - Clinical Neurology and Neuroscience
SP - 29
EP - 32
PB - Science Publishing Group
SN - 2578-8930
UR - https://doi.org/10.11648/j.cnn.20200402.12
AB - Cerebral palsy is a disorder of movement and posture due to disruption of the immature motoric cells in central nervous systems. It is characterized by various neurological abnormalities, one of them is epilepsy. Epilepsy is difficult to control, as it is able to aggravate motor disorders and disrupt cognitive function, ultimately worsening the long-term outcome. This research aims to determine the characteristics of epilepsy in children with cerebral palsy. A cross-sectional study was done based on medical records data Pediatric Outpatient Department and Medical Rehabilitation Installation Sanglah Hospital from January 2016 until June 2018. Eighty-four samples were included. Most of the samples were female (53.6%) with mean of age was 64 months and onset of epilepsy was 21 months. Regarding to nutritional status, most of them with undernutrition (44%). Based on birth history, 66.7% of them was born by spontaneous delivery, 34.5% with asphyxia and 82.1% were normal birth weight. Generalized seizure was the most common type of seizure (81%). Most types of cerebral palsy were spastic type (94%). History of seizures at <1 year of age was 63.1%. History of central nervous system infection was 15.5%. The most brain abnormalities was microcephaly (34.5%). Abnormal EEG results were about 91.7%, with family history of seizures was 1.2%. Frequency of polytherapy with anti-epileptic drugs was 69%. The most common type of cerebral palsy in this research was spastic type. Generalized seizure was the most common type of seizure in epilepsy children with cerebral palsy. Most of them have abnormal EEG results and need more than one anti-epileptic therapy.
VL - 4
IS - 2
ER -

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Author Information

Denis Fiolita

Department of Child Health, Medical Faculty of Udayana University, Sanglah Hospital, Denpasar, Indonesia
I Gusti Ngurah Made Suwarba

Department of Child Health, Medical Faculty of Udayana University, Sanglah Hospital, Denpasar, Indonesia
Dewi Sutriani Mahalini

Department of Child Health, Medical Faculty of Udayana University, Sanglah Hospital, Denpasar, Indonesia

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APA Style

Denis Fiolita, I Gusti Ngurah Made Suwarba, Dewi Sutriani Mahalini. (2020). Characteristics of Epilepsy in Children with Cerebral Palsy. Clinical Neurology and Neuroscience, 4(2), 29-32. https://doi.org/10.11648/j.cnn.20200402.12

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ACS Style

Denis Fiolita; I Gusti Ngurah Made Suwarba; Dewi Sutriani Mahalini. Characteristics of Epilepsy in Children with Cerebral Palsy. Clin. Neurol. Neurosci. 2020, 4(2), 29-32. doi: 10.11648/j.cnn.20200402.12

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AMA Style

Denis Fiolita, I Gusti Ngurah Made Suwarba, Dewi Sutriani Mahalini. Characteristics of Epilepsy in Children with Cerebral Palsy. Clin Neurol Neurosci. 2020;4(2):29-32. doi: 10.11648/j.cnn.20200402.12

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@article{10.11648/j.cnn.20200402.12,
  author = {Denis Fiolita and I Gusti Ngurah Made Suwarba and Dewi Sutriani Mahalini},
  title = {Characteristics of Epilepsy in Children with Cerebral Palsy},
  journal = {Clinical Neurology and Neuroscience},
  volume = {4},
  number = {2},
  pages = {29-32},
  doi = {10.11648/j.cnn.20200402.12},
  url = {https://doi.org/10.11648/j.cnn.20200402.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.cnn.20200402.12},
  abstract = {Cerebral palsy is a disorder of movement and posture due to disruption of the immature motoric cells in central nervous systems. It is characterized by various neurological abnormalities, one of them is epilepsy. Epilepsy is difficult to control, as it is able to aggravate motor disorders and disrupt cognitive function, ultimately worsening the long-term outcome. This research aims to determine the characteristics of epilepsy in children with cerebral palsy. A cross-sectional study was done based on medical records data Pediatric Outpatient Department and Medical Rehabilitation Installation Sanglah Hospital from January 2016 until June 2018. Eighty-four samples were included. Most of the samples were female (53.6%) with mean of age was 64 months and onset of epilepsy was 21 months. Regarding to nutritional status, most of them with undernutrition (44%). Based on birth history, 66.7% of them was born by spontaneous delivery, 34.5% with asphyxia and 82.1% were normal birth weight. Generalized seizure was the most common type of seizure (81%). Most types of cerebral palsy were spastic type (94%). History of seizures at <1 year of age was 63.1%. History of central nervous system infection was 15.5%. The most brain abnormalities was microcephaly (34.5%). Abnormal EEG results were about 91.7%, with family history of seizures was 1.2%. Frequency of polytherapy with anti-epileptic drugs was 69%. The most common type of cerebral palsy in this research was spastic type. Generalized seizure was the most common type of seizure in epilepsy children with cerebral palsy. Most of them have abnormal EEG results and need more than one anti-epileptic therapy.},
 year = {2020}
}

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