Pure Agraphia Associated with a Frontal Meningioma on Left Superior Frontal Gyrus

Franck-Emmanuel Roux; Imène Djidjeli; Julien Nicolau; Jean Darcourt; Florian Le Lann; Jean-François Demonet

doi:doi:10.11648/j.cnn.20210504.11

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Pure Agraphia Associated with a Frontal Meningioma on Left Superior Frontal Gyrus

Franck-Emmanuel Roux, Imène Djidjeli, Julien Nicolau, Jean Darcourt, Florian Le Lann, Jean-François Demonet

Published in Clinical Neurology and Neuroscience (Volume 5, Issue 4)

Received: 1 September 2021 Accepted: 22 September 2021 Published: 30 September 2021

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Abstract

Background: The existence of cerebral area specifically involved in coding for writing movements in the left middle frontal gyrus is a matter of debate. We present a rare case of pure agraphia associated with a left frontal meningioma. The location of the lesion associated with this disorder could help to feed this debate. Method: We report a case of pure agraphia in a 69-year-old man. The patient had a writing disorder evolving over several months with a dominant, left frontal lesion. On neuropsychological evaluation, the writing difficulties were present whatever the nature of the writing (spontaneous, dictation, coping). The writing disorder was isolated, with no features of aphasia, alexia or limb apraxia. Phonological and lexical processing was preserved. The imaging showed a probable frontal meningioma restricted to the foot of the first and second left frontal circumvolutions (MNI coordinates /barycenter of the lesion: x=-19.8, y=1.5, z=52.2). Results: The patient was operated and the whole lesion was removed. After surgical resection, the patient’s writing disorder improved. Other components of language assessed were the same as before the surgery and showed no disturbances. The pathological study concluded on an OMS grade II atypical meningioma. Conclusion: We think that the disorder presented by our patient was related to the disturbance of the frontal graphemic center located in the Exner area. Here, we describe and analyze his condition through a neuro-anatomical and a cognitive approach.

Published in	Clinical Neurology and Neuroscience (Volume 5, Issue 4)
DOI	10.11648/j.cnn.20210504.11
Page(s)	72-77
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2021. Published by Science Publishing Group

Keywords

Agraphia, Exner, Frontal Graphemic Center

References

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Franck-Emmanuel Roux, Imène Djidjeli, Julien Nicolau, Jean Darcourt, Florian Le Lann, et al. (2021). Pure Agraphia Associated with a Frontal Meningioma on Left Superior Frontal Gyrus. Clinical Neurology and Neuroscience, 5(4), 72-77. https://doi.org/10.11648/j.cnn.20210504.11

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ACS Style

Franck-Emmanuel Roux; Imène Djidjeli; Julien Nicolau; Jean Darcourt; Florian Le Lann, et al. Pure Agraphia Associated with a Frontal Meningioma on Left Superior Frontal Gyrus. Clin. Neurol. Neurosci. 2021, 5(4), 72-77. doi: 10.11648/j.cnn.20210504.11

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AMA Style

Franck-Emmanuel Roux, Imène Djidjeli, Julien Nicolau, Jean Darcourt, Florian Le Lann, et al. Pure Agraphia Associated with a Frontal Meningioma on Left Superior Frontal Gyrus. Clin Neurol Neurosci. 2021;5(4):72-77. doi: 10.11648/j.cnn.20210504.11

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@article{10.11648/j.cnn.20210504.11,
  author = {Franck-Emmanuel Roux and Imène Djidjeli and Julien Nicolau and Jean Darcourt and Florian Le Lann and Jean-François Demonet},
  title = {Pure Agraphia Associated with a Frontal Meningioma on Left Superior Frontal Gyrus},
  journal = {Clinical Neurology and Neuroscience},
  volume = {5},
  number = {4},
  pages = {72-77},
  doi = {10.11648/j.cnn.20210504.11},
  url = {https://doi.org/10.11648/j.cnn.20210504.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.cnn.20210504.11},
  abstract = {Background: The existence of cerebral area specifically involved in coding for writing movements in the left middle frontal gyrus is a matter of debate. We present a rare case of pure agraphia associated with a left frontal meningioma. The location of the lesion associated with this disorder could help to feed this debate. Method: We report a case of pure agraphia in a 69-year-old man. The patient had a writing disorder evolving over several months with a dominant, left frontal lesion. On neuropsychological evaluation, the writing difficulties were present whatever the nature of the writing (spontaneous, dictation, coping). The writing disorder was isolated, with no features of aphasia, alexia or limb apraxia. Phonological and lexical processing was preserved. The imaging showed a probable frontal meningioma restricted to the foot of the first and second left frontal circumvolutions (MNI coordinates /barycenter of the lesion: x=-19.8, y=1.5, z=52.2). Results: The patient was operated and the whole lesion was removed. After surgical resection, the patient’s writing disorder improved. Other components of language assessed were the same as before the surgery and showed no disturbances. The pathological study concluded on an OMS grade II atypical meningioma. Conclusion: We think that the disorder presented by our patient was related to the disturbance of the frontal graphemic center located in the Exner area. Here, we describe and analyze his condition through a neuro-anatomical and a cognitive approach.},
 year = {2021}
}

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TY - JOUR
T1 - Pure Agraphia Associated with a Frontal Meningioma on Left Superior Frontal Gyrus
AU - Franck-Emmanuel Roux
AU - Imène Djidjeli
AU - Julien Nicolau
AU - Jean Darcourt
AU - Florian Le Lann
AU - Jean-François Demonet
Y1 - 2021/09/30
PY - 2021
N1 - https://doi.org/10.11648/j.cnn.20210504.11
DO - 10.11648/j.cnn.20210504.11
T2 - Clinical Neurology and Neuroscience
JF - Clinical Neurology and Neuroscience
JO - Clinical Neurology and Neuroscience
SP - 72
EP - 77
PB - Science Publishing Group
SN - 2578-8930
UR - https://doi.org/10.11648/j.cnn.20210504.11
AB - Background: The existence of cerebral area specifically involved in coding for writing movements in the left middle frontal gyrus is a matter of debate. We present a rare case of pure agraphia associated with a left frontal meningioma. The location of the lesion associated with this disorder could help to feed this debate. Method: We report a case of pure agraphia in a 69-year-old man. The patient had a writing disorder evolving over several months with a dominant, left frontal lesion. On neuropsychological evaluation, the writing difficulties were present whatever the nature of the writing (spontaneous, dictation, coping). The writing disorder was isolated, with no features of aphasia, alexia or limb apraxia. Phonological and lexical processing was preserved. The imaging showed a probable frontal meningioma restricted to the foot of the first and second left frontal circumvolutions (MNI coordinates /barycenter of the lesion: x=-19.8, y=1.5, z=52.2). Results: The patient was operated and the whole lesion was removed. After surgical resection, the patient’s writing disorder improved. Other components of language assessed were the same as before the surgery and showed no disturbances. The pathological study concluded on an OMS grade II atypical meningioma. Conclusion: We think that the disorder presented by our patient was related to the disturbance of the frontal graphemic center located in the Exner area. Here, we describe and analyze his condition through a neuro-anatomical and a cognitive approach.
VL - 5
IS - 4
ER -

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Author Information

Franck-Emmanuel Roux

CNRS (CERCO) Unity 5549, Paul Sabatier Faculty, University Hospital Center, Toulouse, France
Imène Djidjeli

CNRS (CERCO) Unity 5549, Paul Sabatier Faculty, University Hospital Center, Toulouse, France
Julien Nicolau

Department of Neurosurgery, NeuroSciences, University Hospital Center of Pierre-Paul Riquet, Toulouse, France
Jean Darcourt

Department de Neuroradiology, NeuroSciences, University Hospital Center of Pierre-Paul Riquet, Toulouse, France
Florian Le Lann

Department of Neurosurgery, NeuroSciences, University Hospital Center of Pierre-Paul Riquet, Toulouse, France
Jean-François Demonet

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Franck-Emmanuel Roux, Imène Djidjeli, Julien Nicolau, Jean Darcourt, Florian Le Lann, et al. (2021). Pure Agraphia Associated with a Frontal Meningioma on Left Superior Frontal Gyrus. Clinical Neurology and Neuroscience, 5(4), 72-77. https://doi.org/10.11648/j.cnn.20210504.11

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ACS Style

Franck-Emmanuel Roux; Imène Djidjeli; Julien Nicolau; Jean Darcourt; Florian Le Lann, et al. Pure Agraphia Associated with a Frontal Meningioma on Left Superior Frontal Gyrus. Clin. Neurol. Neurosci. 2021, 5(4), 72-77. doi: 10.11648/j.cnn.20210504.11

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AMA Style

Franck-Emmanuel Roux, Imène Djidjeli, Julien Nicolau, Jean Darcourt, Florian Le Lann, et al. Pure Agraphia Associated with a Frontal Meningioma on Left Superior Frontal Gyrus. Clin Neurol Neurosci. 2021;5(4):72-77. doi: 10.11648/j.cnn.20210504.11

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@article{10.11648/j.cnn.20210504.11,
  author = {Franck-Emmanuel Roux and Imène Djidjeli and Julien Nicolau and Jean Darcourt and Florian Le Lann and Jean-François Demonet},
  title = {Pure Agraphia Associated with a Frontal Meningioma on Left Superior Frontal Gyrus},
  journal = {Clinical Neurology and Neuroscience},
  volume = {5},
  number = {4},
  pages = {72-77},
  doi = {10.11648/j.cnn.20210504.11},
  url = {https://doi.org/10.11648/j.cnn.20210504.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.cnn.20210504.11},
  abstract = {Background: The existence of cerebral area specifically involved in coding for writing movements in the left middle frontal gyrus is a matter of debate. We present a rare case of pure agraphia associated with a left frontal meningioma. The location of the lesion associated with this disorder could help to feed this debate. Method: We report a case of pure agraphia in a 69-year-old man. The patient had a writing disorder evolving over several months with a dominant, left frontal lesion. On neuropsychological evaluation, the writing difficulties were present whatever the nature of the writing (spontaneous, dictation, coping). The writing disorder was isolated, with no features of aphasia, alexia or limb apraxia. Phonological and lexical processing was preserved. The imaging showed a probable frontal meningioma restricted to the foot of the first and second left frontal circumvolutions (MNI coordinates /barycenter of the lesion: x=-19.8, y=1.5, z=52.2). Results: The patient was operated and the whole lesion was removed. After surgical resection, the patient’s writing disorder improved. Other components of language assessed were the same as before the surgery and showed no disturbances. The pathological study concluded on an OMS grade II atypical meningioma. Conclusion: We think that the disorder presented by our patient was related to the disturbance of the frontal graphemic center located in the Exner area. Here, we describe and analyze his condition through a neuro-anatomical and a cognitive approach.},
 year = {2021}
}

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