Microscope images analysis of erythrocyte (red blood cells, RBCs) was a widely used method for medical purpose. Usually manual measuring and analysis of the images were subject to time-consuming, errors and unstability of results. The images analysis method had been combined with computer image processing techniques in this research. A measuring and analysis system for microscope images(MIAS) of RBCs was developed, which could recognize RBCs in images and measure cells mophometric parameters. Normal human RBCs were compared with ones under high glucose. The results indicated RBCs sizes parameters such as areas, perimeters, major axis lengths, minor axis lengths, elongations, roundnesses and Feret diameters have difference between normal and high glucose conditions. RBCs normal disk shapes changed into acanthocyte and stomatocyte under higher glucose conditions. This fast and precise method for measuring RBCs morphometric parameters contributed to pathogenesis of diabetic nephropathy(DN) research.
| Published in | International Journal of Biomedical Science and Engineering (Volume 4, Issue 3) |
| DOI | 10.11648/j.ijbse.20160403.12 |
| Page(s) | 22-27 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2016. Published by Science Publishing Group |
Diabetic Nephropathy, Microscope Image Analysis, Morphological Characteristics
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APA Style
Bohua Feng, Liufen Peng. (2016). Erythrocyte Morphological Characteristics Based on Microscope Images System. International Journal of Biomedical Science and Engineering, 4(3), 22-27. https://doi.org/10.11648/j.ijbse.20160403.12
ACS Style
Bohua Feng; Liufen Peng. Erythrocyte Morphological Characteristics Based on Microscope Images System. Int. J. Biomed. Sci. Eng. 2016, 4(3), 22-27. doi: 10.11648/j.ijbse.20160403.12
AMA Style
Bohua Feng, Liufen Peng. Erythrocyte Morphological Characteristics Based on Microscope Images System. Int J Biomed Sci Eng. 2016;4(3):22-27. doi: 10.11648/j.ijbse.20160403.12
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Download@article{10.11648/j.ijbse.20160403.12,
author = {Bohua Feng and Liufen Peng},
title = {Erythrocyte Morphological Characteristics Based on Microscope Images System},
journal = {International Journal of Biomedical Science and Engineering},
volume = {4},
number = {3},
pages = {22-27},
doi = {10.11648/j.ijbse.20160403.12},
url = {https://doi.org/10.11648/j.ijbse.20160403.12},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijbse.20160403.12},
abstract = {Microscope images analysis of erythrocyte (red blood cells, RBCs) was a widely used method for medical purpose. Usually manual measuring and analysis of the images were subject to time-consuming, errors and unstability of results. The images analysis method had been combined with computer image processing techniques in this research. A measuring and analysis system for microscope images(MIAS) of RBCs was developed, which could recognize RBCs in images and measure cells mophometric parameters. Normal human RBCs were compared with ones under high glucose. The results indicated RBCs sizes parameters such as areas, perimeters, major axis lengths, minor axis lengths, elongations, roundnesses and Feret diameters have difference between normal and high glucose conditions. RBCs normal disk shapes changed into acanthocyte and stomatocyte under higher glucose conditions. This fast and precise method for measuring RBCs morphometric parameters contributed to pathogenesis of diabetic nephropathy(DN) research.},
year = {2016}
}
TY - JOUR T1 - Erythrocyte Morphological Characteristics Based on Microscope Images System AU - Bohua Feng AU - Liufen Peng Y1 - 2016/09/27 PY - 2016 N1 - https://doi.org/10.11648/j.ijbse.20160403.12 DO - 10.11648/j.ijbse.20160403.12 T2 - International Journal of Biomedical Science and Engineering JF - International Journal of Biomedical Science and Engineering JO - International Journal of Biomedical Science and Engineering SP - 22 EP - 27 PB - Science Publishing Group SN - 2376-7235 UR - https://doi.org/10.11648/j.ijbse.20160403.12 AB - Microscope images analysis of erythrocyte (red blood cells, RBCs) was a widely used method for medical purpose. Usually manual measuring and analysis of the images were subject to time-consuming, errors and unstability of results. The images analysis method had been combined with computer image processing techniques in this research. A measuring and analysis system for microscope images(MIAS) of RBCs was developed, which could recognize RBCs in images and measure cells mophometric parameters. Normal human RBCs were compared with ones under high glucose. The results indicated RBCs sizes parameters such as areas, perimeters, major axis lengths, minor axis lengths, elongations, roundnesses and Feret diameters have difference between normal and high glucose conditions. RBCs normal disk shapes changed into acanthocyte and stomatocyte under higher glucose conditions. This fast and precise method for measuring RBCs morphometric parameters contributed to pathogenesis of diabetic nephropathy(DN) research. VL - 4 IS - 3 ER -
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