Relationship Between ABO and Rhesus Blood Groups and Susceptibility to Asthma Within Sokoto Metropolis, Nigeria

Moses Nnaemeka Alo; Ukpai Agwu Eze; Saidu Abdulhi Yaro; Bello Jubril; Nelson Nnanna Nwanoke

doi:doi:10.11648/j.iji.20150303.12

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Relationship Between ABO and Rhesus Blood Groups and Susceptibility to Asthma Within Sokoto Metropolis, Nigeria

Moses Nnaemeka Alo, Ukpai Agwu Eze, Saidu Abdulhi Yaro, Bello Jubril, Nelson Nnanna Nwanoke

Published in International Journal of Immunology (Volume 3, Issue 3)

Received: 25 May 2015 Accepted: 1 June 2015 Published: 16 June 2015

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Abstract

Asthma is the result of chronic inflammation of the airways which subsequently results in increased contractability of the surrounding smooth muscles. This among other factors leads to bouts of narrowing of the airway and the classic symptoms of wheezing. As at 2011, World Health Organisation (WHO) reported that approximately 235 million people worldwide were affected by asthma. This study aims to evaluate and determine the susceptibility of ABO and Rh blood groups to asthma. A total of 200 clinically confirmed asthmatic patients and 100 apparently healthy individuals within Sokoto metropolis were prospectively enrolled and their blood group status were determined using red blood cell agglutination method. In this research work, the result obtained shows that 74 asthmatic patients constituting 37.0% out of the total 200 patients who participated in the study are blood group A, 56 (28.0%) are blood group B, 26 (13.0%) are blood group AB and 44 (22.0%) are blood group O. For Rh blood group, out of the 200 study subjects, 181 (90.5%) are Rh positive and 19 (9.5%) are Rh negative. Among 100 control participants 26 (26.0%) have A blood group, 24 (24.0%) have B blood group, 2 (2.0%) have AB blood group, and 48 (48.0%) have O blood group. No statistical difference was observed between Rh system in study subjects and controls, but blood group A was significantly higher in asthma patients compared to controls (P<0.05).

Published in	International Journal of Immunology (Volume 3, Issue 3)
DOI	10.11648/j.iji.20150303.12
Page(s)	37-41
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2015. Published by Science Publishing Group

Keywords

Asthma, ABO Blood Group, Rhesus Blood Group, Nigeria

References

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APA Style

Moses Nnaemeka Alo, Ukpai Agwu Eze, Saidu Abdulhi Yaro, Bello Jubril, Nelson Nnanna Nwanoke. (2015). Relationship Between ABO and Rhesus Blood Groups and Susceptibility to Asthma Within Sokoto Metropolis, Nigeria. International Journal of Immunology, 3(3), 37-41. https://doi.org/10.11648/j.iji.20150303.12

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ACS Style

Moses Nnaemeka Alo; Ukpai Agwu Eze; Saidu Abdulhi Yaro; Bello Jubril; Nelson Nnanna Nwanoke. Relationship Between ABO and Rhesus Blood Groups and Susceptibility to Asthma Within Sokoto Metropolis, Nigeria. Int. J. Immunol. 2015, 3(3), 37-41. doi: 10.11648/j.iji.20150303.12

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AMA Style

Moses Nnaemeka Alo, Ukpai Agwu Eze, Saidu Abdulhi Yaro, Bello Jubril, Nelson Nnanna Nwanoke. Relationship Between ABO and Rhesus Blood Groups and Susceptibility to Asthma Within Sokoto Metropolis, Nigeria. Int J Immunol. 2015;3(3):37-41. doi: 10.11648/j.iji.20150303.12

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@article{10.11648/j.iji.20150303.12,
  author = {Moses Nnaemeka Alo and Ukpai Agwu Eze and Saidu Abdulhi Yaro and Bello Jubril and Nelson Nnanna Nwanoke},
  title = {Relationship Between ABO and Rhesus Blood Groups and Susceptibility to Asthma Within Sokoto Metropolis, Nigeria},
  journal = {International Journal of Immunology},
  volume = {3},
  number = {3},
  pages = {37-41},
  doi = {10.11648/j.iji.20150303.12},
  url = {https://doi.org/10.11648/j.iji.20150303.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.iji.20150303.12},
  abstract = {Asthma is the result of chronic inflammation of the airways which subsequently results in increased contractability of the surrounding smooth muscles. This among other factors leads to bouts of narrowing of the airway and the classic symptoms of wheezing. As at 2011, World Health Organisation (WHO) reported that approximately 235 million people worldwide were affected by asthma. This study aims to evaluate and determine the susceptibility of ABO and Rh blood groups to asthma. A total of 200 clinically confirmed asthmatic patients and 100 apparently healthy individuals within Sokoto metropolis were prospectively enrolled and their blood group status were determined using red blood cell agglutination method. In this research work, the result obtained shows that 74 asthmatic patients constituting 37.0% out of the total 200 patients who participated in the study are blood group A, 56 (28.0%) are blood group B, 26 (13.0%) are blood group AB and 44 (22.0%) are blood group O. For Rh blood group, out of the 200 study subjects, 181 (90.5%) are Rh positive and 19 (9.5%) are Rh negative. Among 100 control participants 26 (26.0%) have A blood group, 24 (24.0%) have B blood group, 2 (2.0%) have AB blood group, and 48 (48.0%) have O blood group. No statistical difference was observed between Rh system in study subjects and controls, but blood group A was significantly higher in asthma patients compared to controls (P<0.05).},
 year = {2015}
}

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TY  - JOUR
T1  - Relationship Between ABO and Rhesus Blood Groups and Susceptibility to Asthma Within Sokoto Metropolis, Nigeria
AU  - Moses Nnaemeka Alo
AU  - Ukpai Agwu Eze
AU  - Saidu Abdulhi Yaro
AU  - Bello Jubril
AU  - Nelson Nnanna Nwanoke
Y1  - 2015/06/16
PY  - 2015
N1  - https://doi.org/10.11648/j.iji.20150303.12
DO  - 10.11648/j.iji.20150303.12
T2  - International Journal of Immunology
JF  - International Journal of Immunology
JO  - International Journal of Immunology
SP  - 37
EP  - 41
PB  - Science Publishing Group
SN  - 2329-1753
UR  - https://doi.org/10.11648/j.iji.20150303.12
AB  - Asthma is the result of chronic inflammation of the airways which subsequently results in increased contractability of the surrounding smooth muscles. This among other factors leads to bouts of narrowing of the airway and the classic symptoms of wheezing. As at 2011, World Health Organisation (WHO) reported that approximately 235 million people worldwide were affected by asthma. This study aims to evaluate and determine the susceptibility of ABO and Rh blood groups to asthma. A total of 200 clinically confirmed asthmatic patients and 100 apparently healthy individuals within Sokoto metropolis were prospectively enrolled and their blood group status were determined using red blood cell agglutination method. In this research work, the result obtained shows that 74 asthmatic patients constituting 37.0% out of the total 200 patients who participated in the study are blood group A, 56 (28.0%) are blood group B, 26 (13.0%) are blood group AB and 44 (22.0%) are blood group O. For Rh blood group, out of the 200 study subjects, 181 (90.5%) are Rh positive and 19 (9.5%) are Rh negative. Among 100 control participants 26 (26.0%) have A blood group, 24 (24.0%) have B blood group, 2 (2.0%) have AB blood group, and 48 (48.0%) have O blood group. No statistical difference was observed between Rh system in study subjects and controls, but blood group A was significantly higher in asthma patients compared to controls (P<0.05).
VL  - 3
IS  - 3
ER  -

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Author Information

Moses Nnaemeka Alo

Department of Biological Sciences/Microbiology/Biotechnology, Faculty of Science and Technology, Federal University Ndufu-Alike, Ikwo, Ebonyi State, Nigeria
Ukpai Agwu Eze

Department of Medical Laboratory Sciences, Faculty of Health Sciences, Ebonyi State University, Abakaliki, Nigeria
Saidu Abdulhi Yaro

Department of Immunology, Faculty of Medical Laboratory Sciences, Usmanu Danfodio University, Sokoto, Nigeria
Bello Jubril

Department of Immunology, Faculty of Medical Laboratory Sciences, Usmanu Danfodio University, Sokoto, Nigeria
Nelson Nnanna Nwanoke

Department of Chemical Pathology, Federal Teaching Hospital, Abakaliki, Ebonyi State, Nigeria

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APA Style

Moses Nnaemeka Alo, Ukpai Agwu Eze, Saidu Abdulhi Yaro, Bello Jubril, Nelson Nnanna Nwanoke. (2015). Relationship Between ABO and Rhesus Blood Groups and Susceptibility to Asthma Within Sokoto Metropolis, Nigeria. International Journal of Immunology, 3(3), 37-41. https://doi.org/10.11648/j.iji.20150303.12

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ACS Style

Moses Nnaemeka Alo; Ukpai Agwu Eze; Saidu Abdulhi Yaro; Bello Jubril; Nelson Nnanna Nwanoke. Relationship Between ABO and Rhesus Blood Groups and Susceptibility to Asthma Within Sokoto Metropolis, Nigeria. Int. J. Immunol. 2015, 3(3), 37-41. doi: 10.11648/j.iji.20150303.12

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AMA Style

Moses Nnaemeka Alo, Ukpai Agwu Eze, Saidu Abdulhi Yaro, Bello Jubril, Nelson Nnanna Nwanoke. Relationship Between ABO and Rhesus Blood Groups and Susceptibility to Asthma Within Sokoto Metropolis, Nigeria. Int J Immunol. 2015;3(3):37-41. doi: 10.11648/j.iji.20150303.12

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@article{10.11648/j.iji.20150303.12,
  author = {Moses Nnaemeka Alo and Ukpai Agwu Eze and Saidu Abdulhi Yaro and Bello Jubril and Nelson Nnanna Nwanoke},
  title = {Relationship Between ABO and Rhesus Blood Groups and Susceptibility to Asthma Within Sokoto Metropolis, Nigeria},
  journal = {International Journal of Immunology},
  volume = {3},
  number = {3},
  pages = {37-41},
  doi = {10.11648/j.iji.20150303.12},
  url = {https://doi.org/10.11648/j.iji.20150303.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.iji.20150303.12},
  abstract = {Asthma is the result of chronic inflammation of the airways which subsequently results in increased contractability of the surrounding smooth muscles. This among other factors leads to bouts of narrowing of the airway and the classic symptoms of wheezing. As at 2011, World Health Organisation (WHO) reported that approximately 235 million people worldwide were affected by asthma. This study aims to evaluate and determine the susceptibility of ABO and Rh blood groups to asthma. A total of 200 clinically confirmed asthmatic patients and 100 apparently healthy individuals within Sokoto metropolis were prospectively enrolled and their blood group status were determined using red blood cell agglutination method. In this research work, the result obtained shows that 74 asthmatic patients constituting 37.0% out of the total 200 patients who participated in the study are blood group A, 56 (28.0%) are blood group B, 26 (13.0%) are blood group AB and 44 (22.0%) are blood group O. For Rh blood group, out of the 200 study subjects, 181 (90.5%) are Rh positive and 19 (9.5%) are Rh negative. Among 100 control participants 26 (26.0%) have A blood group, 24 (24.0%) have B blood group, 2 (2.0%) have AB blood group, and 48 (48.0%) have O blood group. No statistical difference was observed between Rh system in study subjects and controls, but blood group A was significantly higher in asthma patients compared to controls (P<0.05).},
 year = {2015}
}

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TY  - JOUR
T1  - Relationship Between ABO and Rhesus Blood Groups and Susceptibility to Asthma Within Sokoto Metropolis, Nigeria
AU  - Moses Nnaemeka Alo
AU  - Ukpai Agwu Eze
AU  - Saidu Abdulhi Yaro
AU  - Bello Jubril
AU  - Nelson Nnanna Nwanoke
Y1  - 2015/06/16
PY  - 2015
N1  - https://doi.org/10.11648/j.iji.20150303.12
DO  - 10.11648/j.iji.20150303.12
T2  - International Journal of Immunology
JF  - International Journal of Immunology
JO  - International Journal of Immunology
SP  - 37
EP  - 41
PB  - Science Publishing Group
SN  - 2329-1753
UR  - https://doi.org/10.11648/j.iji.20150303.12
AB  - Asthma is the result of chronic inflammation of the airways which subsequently results in increased contractability of the surrounding smooth muscles. This among other factors leads to bouts of narrowing of the airway and the classic symptoms of wheezing. As at 2011, World Health Organisation (WHO) reported that approximately 235 million people worldwide were affected by asthma. This study aims to evaluate and determine the susceptibility of ABO and Rh blood groups to asthma. A total of 200 clinically confirmed asthmatic patients and 100 apparently healthy individuals within Sokoto metropolis were prospectively enrolled and their blood group status were determined using red blood cell agglutination method. In this research work, the result obtained shows that 74 asthmatic patients constituting 37.0% out of the total 200 patients who participated in the study are blood group A, 56 (28.0%) are blood group B, 26 (13.0%) are blood group AB and 44 (22.0%) are blood group O. For Rh blood group, out of the 200 study subjects, 181 (90.5%) are Rh positive and 19 (9.5%) are Rh negative. Among 100 control participants 26 (26.0%) have A blood group, 24 (24.0%) have B blood group, 2 (2.0%) have AB blood group, and 48 (48.0%) have O blood group. No statistical difference was observed between Rh system in study subjects and controls, but blood group A was significantly higher in asthma patients compared to controls (P<0.05).
VL  - 3
IS  - 3
ER  -

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