Medicinal Plants in Breast Cancer Therapy

Tagne Simo Richard; Armel Herve Nwabo Kamdje; Farah Mukhtar

doi:doi:10.11648/j.jdmp.20150101.13

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Medicinal Plants in Breast Cancer Therapy

Tagne Simo Richard, Armel Herve Nwabo Kamdje, Farah Mukhtar

Published in Journal of Diseases and Medicinal Plants (Volume 1, Issue 1)

Received: 20 April 2015 Accepted: 24 April 2015 Published: 30 April 2015

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Abstract

Various active compounds (or their semi-synthetic derivatives) derived from medicinal plants have been assessed for their efficacy and tolerability in the treatment of breast cancer. Some of these plant species, including Taxus baccata (paclitaxel, docetaxel), Podophyllum peltatum (etoposide), Camptotheca acuminata (camptothecin) and Vinca rosea (vinblastine, vinorelbine) have well recognized antitumour activity in breast cancer, and have been evaluated in clinical trials. For example, results from recent Phase II/III trials have established docetaxel as the most active single agent in the treatment (first or second-line) of advanced metastatic breast cancer. The treatment of breast cancer, the most common malignancy among women worldwide, remains puzzling partly due to the resistance to therapeutics, which associates with the heterogeneity of case clinical presentations, and limits in the current understanding of the pathogenesis of solid cancers. Oxidative stress is closely related to various diseases, including cancer. The human body is exposed to free radicals, which cause oxidative stress. Oxidative stress may lead to gene mutations leading to carcinogenesis. Antioxidants are protector of the body, preventing oxidative stress, by stabilizing free radicals. Plants are good and cheap sources for the prevention and treatment of oxidative stress and cancer. Major drawbacks to Antioxidant from plants -based therapy and use in breast cancer are herein briefly discussed.

Published in	Journal of Diseases and Medicinal Plants (Volume 1, Issue 1)
DOI	10.11648/j.jdmp.20150101.13
Page(s)	19-23
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2015. Published by Science Publishing Group

Keywords

Medicinal Plants, Natural products, Breast Cancer, Therapy, Anticancer, Free radicals, Antioxidant, Oxidative Stress, Carcinogenesis

References

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APA Style

Tagne Simo Richard, Armel Herve Nwabo Kamdje, Farah Mukhtar. (2015). Medicinal Plants in Breast Cancer Therapy. Journal of Diseases and Medicinal Plants, 1(1), 19-23. https://doi.org/10.11648/j.jdmp.20150101.13

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ACS Style

Tagne Simo Richard; Armel Herve Nwabo Kamdje; Farah Mukhtar. Medicinal Plants in Breast Cancer Therapy. J. Dis. Med. Plants 2015, 1(1), 19-23. doi: 10.11648/j.jdmp.20150101.13

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AMA Style

Tagne Simo Richard, Armel Herve Nwabo Kamdje, Farah Mukhtar. Medicinal Plants in Breast Cancer Therapy. J Dis Med Plants. 2015;1(1):19-23. doi: 10.11648/j.jdmp.20150101.13

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@article{10.11648/j.jdmp.20150101.13,
  author = {Tagne Simo Richard and Armel Herve Nwabo Kamdje and Farah Mukhtar},
  title = {Medicinal Plants in Breast Cancer Therapy},
  journal = {Journal of Diseases and Medicinal Plants},
  volume = {1},
  number = {1},
  pages = {19-23},
  doi = {10.11648/j.jdmp.20150101.13},
  url = {https://doi.org/10.11648/j.jdmp.20150101.13},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.jdmp.20150101.13},
  abstract = {Various active compounds (or their semi-synthetic derivatives) derived from medicinal plants have been assessed for their efficacy and tolerability in the treatment of breast cancer. Some of these plant species, including Taxus baccata (paclitaxel, docetaxel), Podophyllum peltatum (etoposide), Camptotheca acuminata (camptothecin) and Vinca rosea (vinblastine, vinorelbine) have well recognized antitumour activity in breast cancer, and have been evaluated in clinical trials. For example, results from recent Phase II/III trials have established docetaxel as the most active single agent in the treatment (first or second-line) of advanced metastatic breast cancer. The treatment of breast cancer, the most common malignancy among women worldwide, remains puzzling partly due to the resistance to therapeutics, which associates with the heterogeneity of case clinical presentations, and limits in the current understanding of the pathogenesis of solid cancers. Oxidative stress is closely related to various diseases, including cancer. The human body is exposed to free radicals, which cause oxidative stress. Oxidative stress may lead to gene mutations leading to carcinogenesis. Antioxidants are protector of the body, preventing oxidative stress, by stabilizing free radicals. Plants are good and cheap sources for the prevention and treatment of oxidative stress and cancer.  Major drawbacks to Antioxidant from plants -based therapy and use in breast cancer are herein briefly discussed.},
 year = {2015}
}

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TY  - JOUR
T1  - Medicinal Plants in Breast Cancer Therapy
AU  - Tagne Simo Richard
AU  - Armel Herve Nwabo Kamdje
AU  - Farah Mukhtar
Y1  - 2015/04/30
PY  - 2015
N1  - https://doi.org/10.11648/j.jdmp.20150101.13
DO  - 10.11648/j.jdmp.20150101.13
T2  - Journal of Diseases and Medicinal Plants
JF  - Journal of Diseases and Medicinal Plants
JO  - Journal of Diseases and Medicinal Plants
SP  - 19
EP  - 23
PB  - Science Publishing Group
SN  - 2469-8210
UR  - https://doi.org/10.11648/j.jdmp.20150101.13
AB  - Various active compounds (or their semi-synthetic derivatives) derived from medicinal plants have been assessed for their efficacy and tolerability in the treatment of breast cancer. Some of these plant species, including Taxus baccata (paclitaxel, docetaxel), Podophyllum peltatum (etoposide), Camptotheca acuminata (camptothecin) and Vinca rosea (vinblastine, vinorelbine) have well recognized antitumour activity in breast cancer, and have been evaluated in clinical trials. For example, results from recent Phase II/III trials have established docetaxel as the most active single agent in the treatment (first or second-line) of advanced metastatic breast cancer. The treatment of breast cancer, the most common malignancy among women worldwide, remains puzzling partly due to the resistance to therapeutics, which associates with the heterogeneity of case clinical presentations, and limits in the current understanding of the pathogenesis of solid cancers. Oxidative stress is closely related to various diseases, including cancer. The human body is exposed to free radicals, which cause oxidative stress. Oxidative stress may lead to gene mutations leading to carcinogenesis. Antioxidants are protector of the body, preventing oxidative stress, by stabilizing free radicals. Plants are good and cheap sources for the prevention and treatment of oxidative stress and cancer.  Major drawbacks to Antioxidant from plants -based therapy and use in breast cancer are herein briefly discussed.
VL  - 1
IS  - 1
ER  -

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Author Information

Tagne Simo Richard

Department of Biomedical Sciences, University of Ngaoundere, Ngaoundere, Cameroon
Armel Herve Nwabo Kamdje

Department of Biomedical Sciences, University of Ngaoundere, Ngaoundere, Cameroon
Farah Mukhtar

Department of International Center for Chemical and Biological Sciences, University of Karachi, Karachi, Pakistan

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Plain Text BibTeX RIS

APA Style

Tagne Simo Richard, Armel Herve Nwabo Kamdje, Farah Mukhtar. (2015). Medicinal Plants in Breast Cancer Therapy. Journal of Diseases and Medicinal Plants, 1(1), 19-23. https://doi.org/10.11648/j.jdmp.20150101.13

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ACS Style

Tagne Simo Richard; Armel Herve Nwabo Kamdje; Farah Mukhtar. Medicinal Plants in Breast Cancer Therapy. J. Dis. Med. Plants 2015, 1(1), 19-23. doi: 10.11648/j.jdmp.20150101.13

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AMA Style

Tagne Simo Richard, Armel Herve Nwabo Kamdje, Farah Mukhtar. Medicinal Plants in Breast Cancer Therapy. J Dis Med Plants. 2015;1(1):19-23. doi: 10.11648/j.jdmp.20150101.13

Copy | Download

@article{10.11648/j.jdmp.20150101.13,
  author = {Tagne Simo Richard and Armel Herve Nwabo Kamdje and Farah Mukhtar},
  title = {Medicinal Plants in Breast Cancer Therapy},
  journal = {Journal of Diseases and Medicinal Plants},
  volume = {1},
  number = {1},
  pages = {19-23},
  doi = {10.11648/j.jdmp.20150101.13},
  url = {https://doi.org/10.11648/j.jdmp.20150101.13},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.jdmp.20150101.13},
  abstract = {Various active compounds (or their semi-synthetic derivatives) derived from medicinal plants have been assessed for their efficacy and tolerability in the treatment of breast cancer. Some of these plant species, including Taxus baccata (paclitaxel, docetaxel), Podophyllum peltatum (etoposide), Camptotheca acuminata (camptothecin) and Vinca rosea (vinblastine, vinorelbine) have well recognized antitumour activity in breast cancer, and have been evaluated in clinical trials. For example, results from recent Phase II/III trials have established docetaxel as the most active single agent in the treatment (first or second-line) of advanced metastatic breast cancer. The treatment of breast cancer, the most common malignancy among women worldwide, remains puzzling partly due to the resistance to therapeutics, which associates with the heterogeneity of case clinical presentations, and limits in the current understanding of the pathogenesis of solid cancers. Oxidative stress is closely related to various diseases, including cancer. The human body is exposed to free radicals, which cause oxidative stress. Oxidative stress may lead to gene mutations leading to carcinogenesis. Antioxidants are protector of the body, preventing oxidative stress, by stabilizing free radicals. Plants are good and cheap sources for the prevention and treatment of oxidative stress and cancer.  Major drawbacks to Antioxidant from plants -based therapy and use in breast cancer are herein briefly discussed.},
 year = {2015}
}

Copy | Download

TY  - JOUR
T1  - Medicinal Plants in Breast Cancer Therapy
AU  - Tagne Simo Richard
AU  - Armel Herve Nwabo Kamdje
AU  - Farah Mukhtar
Y1  - 2015/04/30
PY  - 2015
N1  - https://doi.org/10.11648/j.jdmp.20150101.13
DO  - 10.11648/j.jdmp.20150101.13
T2  - Journal of Diseases and Medicinal Plants
JF  - Journal of Diseases and Medicinal Plants
JO  - Journal of Diseases and Medicinal Plants
SP  - 19
EP  - 23
PB  - Science Publishing Group
SN  - 2469-8210
UR  - https://doi.org/10.11648/j.jdmp.20150101.13
AB  - Various active compounds (or their semi-synthetic derivatives) derived from medicinal plants have been assessed for their efficacy and tolerability in the treatment of breast cancer. Some of these plant species, including Taxus baccata (paclitaxel, docetaxel), Podophyllum peltatum (etoposide), Camptotheca acuminata (camptothecin) and Vinca rosea (vinblastine, vinorelbine) have well recognized antitumour activity in breast cancer, and have been evaluated in clinical trials. For example, results from recent Phase II/III trials have established docetaxel as the most active single agent in the treatment (first or second-line) of advanced metastatic breast cancer. The treatment of breast cancer, the most common malignancy among women worldwide, remains puzzling partly due to the resistance to therapeutics, which associates with the heterogeneity of case clinical presentations, and limits in the current understanding of the pathogenesis of solid cancers. Oxidative stress is closely related to various diseases, including cancer. The human body is exposed to free radicals, which cause oxidative stress. Oxidative stress may lead to gene mutations leading to carcinogenesis. Antioxidants are protector of the body, preventing oxidative stress, by stabilizing free radicals. Plants are good and cheap sources for the prevention and treatment of oxidative stress and cancer.  Major drawbacks to Antioxidant from plants -based therapy and use in breast cancer are herein briefly discussed.
VL  - 1
IS  - 1
ER  -

Copy | Download