New knowledge about crystallization has surfaced recently, since some of the last lipocryolysis publications have focused on how it works [4, 5]. However, although its action is better understood day after day, there is a sense of feeling that its clinical outcome could be improved. Kinetic particularities of crystal formation process allowed us to think that the cooling speed might be determinant in the results achieved in a lipocryolysis session. Adipocytes from six male rats where isolated and then exposed to 1ºC/min, 2ºC/min and 6ºC/min cooling speeds until they reached 8ºC and were kept at that temperature for 30 minutes. Cell damage was significantly higher in 1ºC/min cooling speed than in other cooling speeds.
| Published in |
Journal of Surgery (Volume 3, Issue 1-1)
This article belongs to the Special Issue Breakthroughs in Aesthetic Medicine |
| DOI | 10.11648/j.js.s.2015030101.14 |
| Page(s) | 11-13 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2014. Published by Science Publishing Group |
Lipocryolysis, Cooling Speed, Adipocyte
| [1] | Pinto H, Arredondo E, Ricart-Jané D. Study for the Evaluation of Adipocytic Changes after a Simil-Lipocryolysis Stimulus. Cryoletters 34(1) (2013)100-5 |
| [2] | Pinto H, Pardina E, Ricart-Jané D. X-ray diffraction analysis confirms intra-adipocitary lipid crystallization after a lipocryolysis-like stimulus. Cryoletters 34(6) (2013) 619-23 |
| [3] | Pinto H, Pardina E, Ricart-Jané D. X-ray diffraction analysis confirms intra-adipocitary lipid crystallization after a lipocryolysis-like stimulus. Cryoletters 34(6) (2013) 619-23 |
| [4] | Coleman S, Sachdeva K, Egbert B, Preciado JA, Allison J. Clinical efficacy of non-invasive Cryolipolysis™ and its effects on peripheral nerves AesthPlast Surg 33(2009) 482–8 |
| [5] | Pinto H, García-Cruz E, Melamed G. Study to Evaluate the Action of Lipocryolysis. Cryoletters 33(3) (2013):176-80 |
| [6] | Manstein D, Laubach H, Watannabe K, Farinelli W, ZurakowskiD, Anderson RR. Selective cryolysis: a novel method of non-invasive fat reduction. Las in Surg and Med 40(2008)595-604 |
| [7] | Zelickson B, Egbert B, Preciado JA, Allison J, Springer K, Manstein D. Cryolipolysis™ for noninvasive fat cell destruction: initial results from a pig model. Dermatol Surg 35(10) (2009) 1462–70 |
APA Style
Hernán Pinto, David Ricart-Jané, Eva Pardina, Graciela Melamed. (2014). Lipocryolysis: Cooling Speed Affects Adipocyte Survival. Journal of Surgery, 3(1-1), 11-13. https://doi.org/10.11648/j.js.s.2015030101.14
ACS Style
Hernán Pinto; David Ricart-Jané; Eva Pardina; Graciela Melamed. Lipocryolysis: Cooling Speed Affects Adipocyte Survival. J. Surg. 2014, 3(1-1), 11-13. doi: 10.11648/j.js.s.2015030101.14
AMA Style
Hernán Pinto, David Ricart-Jané, Eva Pardina, Graciela Melamed. Lipocryolysis: Cooling Speed Affects Adipocyte Survival. J Surg. 2014;3(1-1):11-13. doi: 10.11648/j.js.s.2015030101.14
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Download@article{10.11648/j.js.s.2015030101.14,
author = {Hernán Pinto and David Ricart-Jané and Eva Pardina and Graciela Melamed},
title = {Lipocryolysis: Cooling Speed Affects Adipocyte Survival},
journal = {Journal of Surgery},
volume = {3},
number = {1-1},
pages = {11-13},
doi = {10.11648/j.js.s.2015030101.14},
url = {https://doi.org/10.11648/j.js.s.2015030101.14},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.js.s.2015030101.14},
abstract = {New knowledge about crystallization has surfaced recently, since some of the last lipocryolysis publications have focused on how it works [4, 5]. However, although its action is better understood day after day, there is a sense of feeling that its clinical outcome could be improved. Kinetic particularities of crystal formation process allowed us to think that the cooling speed might be determinant in the results achieved in a lipocryolysis session. Adipocytes from six male rats where isolated and then exposed to 1ºC/min, 2ºC/min and 6ºC/min cooling speeds until they reached 8ºC and were kept at that temperature for 30 minutes. Cell damage was significantly higher in 1ºC/min cooling speed than in other cooling speeds.},
year = {2014}
}
TY - JOUR T1 - Lipocryolysis: Cooling Speed Affects Adipocyte Survival AU - Hernán Pinto AU - David Ricart-Jané AU - Eva Pardina AU - Graciela Melamed Y1 - 2014/12/31 PY - 2014 N1 - https://doi.org/10.11648/j.js.s.2015030101.14 DO - 10.11648/j.js.s.2015030101.14 T2 - Journal of Surgery JF - Journal of Surgery JO - Journal of Surgery SP - 11 EP - 13 PB - Science Publishing Group SN - 2330-0930 UR - https://doi.org/10.11648/j.js.s.2015030101.14 AB - New knowledge about crystallization has surfaced recently, since some of the last lipocryolysis publications have focused on how it works [4, 5]. However, although its action is better understood day after day, there is a sense of feeling that its clinical outcome could be improved. Kinetic particularities of crystal formation process allowed us to think that the cooling speed might be determinant in the results achieved in a lipocryolysis session. Adipocytes from six male rats where isolated and then exposed to 1ºC/min, 2ºC/min and 6ºC/min cooling speeds until they reached 8ºC and were kept at that temperature for 30 minutes. Cell damage was significantly higher in 1ºC/min cooling speed than in other cooling speeds. VL - 3 IS - 1-1 ER -
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