Microalbuminuria in Diabetic Patients in the Bamenda Health District

Marie Ebob Agbortabot Bissong; Gerald Ngo Teke; Moses Samje; Harris Goneh; Frank Eric Tatsing Foka; Henri-Lucien Kamga

doi:doi:10.11648/j.sjcm.20170604.14

| Peer-Reviewed

Microalbuminuria in Diabetic Patients in the Bamenda Health District

Marie Ebob Agbortabot Bissong, Gerald Ngo Teke, Moses Samje, Harris Goneh, Frank Eric Tatsing Foka, Henri-Lucien Kamga

Published in Science Journal of Clinical Medicine (Volume 6, Issue 4)

Received: 15 March 2017 Accepted: 19 April 2017 Published: 18 October 2017

Views: Downloads:

Download PDF

Share This Article

Twitter
Linked In
Facebook

Abstract

Diabetic nephropathy (DN) is the most common cause of end stage renal disease (ESRD) and it accounts for one third of all patients requiring renal replacement therapy in Africa. Diabetic patients with microalbuminuria (MA) have an increased risk of progression to macroalbuminuria and later to ESRD. So detecting MA which is a marker of DN helps to alert the clinician to intervene at a time when future renal damage is still preventable. The main goal of this study was to determine the prevalence of MA in diabetic patients at the Bamenda Regional Hospital. This study was a prospective cross sectional study involving diabetic patients at the Bamenda Regional Hospital. A random (spot) or first morning urine specimen was collected and MA was measured by a semi quantitative dipstick method using the URS-14H urine test strips. The prevalence of MA in the present study was 34.6%, which is high but similar to the results of other studies done in sub-Saharan Africa. Although MA was more common (50%) in individuals with diabetes more than 16 years, a high proportion (42.85%) of patients with MA had a duration of diabetes of ≤ 5years. There was no significant difference in the occurrence of MA with respect to age, gender and duration of diabetes. This study showed a high prevalence of MA in the diabetic population presenting at the Bamenda Regional Hospital. Consequently, measures of glycemic control should be enhanced in this population to prevent the progression to macroalbuminuria and ESRD.

Published in	Science Journal of Clinical Medicine (Volume 6, Issue 4)
DOI	10.11648/j.sjcm.20170604.14
Page(s)	63-67
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2017. Published by Science Publishing Group

Keywords

Microalbuminuria, Diabetes Mellitus, Diabetic Nephropathy, Prevalence, Biomarker

References

[1]	World Health Organization. 1999. “Diabetes and classification of diabetes mellitus, part 1”. pg 2
[2]	E. Loghmani, “Diabetes mellitus: type 1 and type 2” chapter 14 in, Stang, J. Story M (eds). Guidelines for Adolescent Nutrition Services (2005) pg167 assessed on 24-11-2015 URL:http://www.epi.umn.edu/let/pubs/adol_book.shtm
[3]	E. Sobngwi, J. C. Mbanya, E. N. Moukouri, K. B. Ngu “Microalbuminuria and retinopathy in a diabetic population of Cameroon” Diabetes Res. Clin. Pract, 1999, 44(3), 191-6.
[4]	B. Vujičić, T. Turk, Z. Crnčević-Orlić, G. Đorđević, S. Rački, “Diabetic Nephropathy” In Tech 2012. http://dx.doi.org/10.5772/50115. Accessed on 10/12/2015.
[5]	P. Bhoomika, H. A. Dadhania-Amit, A. D. Gauravi “Study of microalbuminuria in diabetes type 2 patients as a marker of morbidity”. IJBAR, 2012, 3(10), 763.
[6]	T. Zelmanovitz, A. F. Gerchman, P. S. Balthazar, C. S. Fúlvio, J. Thomazelli, D. Matos, L. H. Canani “Diabetic nephropathy. Diabetology & Metabolic Syndrome” 2009, 1(10). http://www.dmsjournal.com/content/1/1/10 accessed on 10/12/2015.
[7]	W. Sheldon, P. A. Tobe, D. McFarlane, M. Naimark “Microalbuminuria in diabetes mellitus”. CMAJ, 2002, 167 (5), 499-502.
[8]	D. Parchwani, S. P. Singh “Microalbuminuria in diabetes patients: Prevalence and putative risk factors” Nat. J. Com. Med, 2011, 2(1), 126.
[9]	A. Abdalkader, H. Faris Al Lami “Prevalence and determinants of microalbuminurea among type 2 diabetes mellitus patients, Baghdad, Iraq”. Saudi J. Kidney Dis. Transpl, 2013, 27, 348-55.
[10]	M. M. Lloyd, J. Kuyl, H. Van Jaarsveld “Evaluation of point of care test for detecting microalbuminuria in diabetic patients”. S. Afr. Fam. Pract, 2011, 53(3), 281-286
[11]	J. J. Noubiap, J. Naidoo, A. P. Kengne “Diabetic nephropathy in Africa: A systematic review”, World J. Diabetes, 2015, 10, 6(5). 759-773.
[12]	S. A. Khudhair “Prevalence of Microalbuminuria In Diabetic Patients In Al-Najaf City. Kufa” Med. Journal, 2009, 12(1), 462.
[13]	S. P. Choukem, E. Sobngwi, P. Boudou, L. S. Fetita, R. Porcher, I. Fidaa, B. Blondeau, P. Vexiau, F. Mauvais-Jarvis, F. Calvo J. F. “Gautier “β- and α-Cell Dysfunctions in Africans with Ketosis-Prone Atypical Diabetes During Near-Normoglycemic Remission” Diabetes Care, 2013, 36 (1), 118–123.
[14]	M. N. Elbagir, M. A. Eltom, H. Rosling, C. Berne “Glycaemic Control of Insulin-Dependent Diabetes Mellitus in Sudan: Influence of Insulin Shortage” Diabetes Res. Clin. Pract, 1995, 30 (1), 43–52.
[15]	B. A. Eghan Jr, M. T. Frempong and M. Adjei-Poku “Prevalence and predictors of microalbuminuria in patients with diabetes mellitus: a cross-sectional observational study in Kumasi, Ghana” Ethnicity & Disease, 2007, 7(1), 726-730.
[16]	K. Luthale, J. Joy, T. Hrafenkell, A. G. Zulfiqarali, V. Kåre “Microalbuminuria among Type 1 and Type 2 diabetic patients of African origin in Dar Es Salaam, Tanzania”, BMC Nephrol, 2007, 8(2). http://www.biomedcentral.com/1471-2369/8/2.
[17]	S. Ghosh, I. Lyaruu, K. Yeates “Prevalence and factors associated with microalbuminuria in type 2 diabetic patients at a diabetes clinic in northern Tanzania”. Afr. J. Diabetes Med, 2012, 20(2), 43.
[18]	P. Khan, M. Khan, W. Khan, A. Aziz and A. Ahad “Relationship of Glycemic Control with Prevalence of Microalbuminuria in Diabetic Patients” Gomal J. Med. Sci, 2012, 10(2), 201-204.
[19]	M. Sigdel, N. Rajbhandari, S. Basnet, A. Nagila, P. Basnet, B. K. Tamrakar “Microalbuminuria amongtype 2 diabetes mellitus patients in Pokhara, Nepal” Nepal Med. Coll. J, 2008, 10, 242-5.
[20]	M. T. Pruijm, G. Madeline, W. F. Rieson, M. Burnier, P. Bovet “Prevalence of microalbuminuria in the general population of Seychelles and strong association with diabetes and hypertension independent of renal markers” J. Hypertens, 2008, 26, 871-7.

Cite This Article

Plain Text BibTeX RIS

APA Style

Marie Ebob Agbortabot Bissong, Gerald Ngo Teke, Moses Samje, Harris Goneh, Frank Eric Tatsing Foka, et al. (2017). Microalbuminuria in Diabetic Patients in the Bamenda Health District. Science Journal of Clinical Medicine, 6(4), 63-67. https://doi.org/10.11648/j.sjcm.20170604.14

Copy | Download

ACS Style

Marie Ebob Agbortabot Bissong; Gerald Ngo Teke; Moses Samje; Harris Goneh; Frank Eric Tatsing Foka, et al. Microalbuminuria in Diabetic Patients in the Bamenda Health District. Sci. J. Clin. Med. 2017, 6(4), 63-67. doi: 10.11648/j.sjcm.20170604.14

Copy | Download

AMA Style

Marie Ebob Agbortabot Bissong, Gerald Ngo Teke, Moses Samje, Harris Goneh, Frank Eric Tatsing Foka, et al. Microalbuminuria in Diabetic Patients in the Bamenda Health District. Sci J Clin Med. 2017;6(4):63-67. doi: 10.11648/j.sjcm.20170604.14

Copy | Download

@article{10.11648/j.sjcm.20170604.14,
  author = {Marie Ebob Agbortabot Bissong and Gerald Ngo Teke and Moses Samje and Harris Goneh and Frank Eric Tatsing Foka and Henri-Lucien Kamga},
  title = {Microalbuminuria in Diabetic Patients in the Bamenda Health District},
  journal = {Science Journal of Clinical Medicine},
  volume = {6},
  number = {4},
  pages = {63-67},
  doi = {10.11648/j.sjcm.20170604.14},
  url = {https://doi.org/10.11648/j.sjcm.20170604.14},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.sjcm.20170604.14},
  abstract = {Diabetic nephropathy (DN) is the most common cause of end stage renal disease (ESRD) and it accounts for one third of all patients requiring renal replacement therapy in Africa. Diabetic patients with microalbuminuria (MA) have an increased risk of progression to macroalbuminuria and later to ESRD. So detecting MA which is a marker of DN helps to alert the clinician to intervene at a time when future renal damage is still preventable. The main goal of this study was to determine the prevalence of MA in diabetic patients at the Bamenda Regional Hospital. This study was a prospective cross sectional study involving diabetic patients at the Bamenda Regional Hospital. A random (spot) or first morning urine specimen was collected and MA was measured by a semi quantitative dipstick method using the URS-14H urine test strips. The prevalence of MA in the present study was 34.6%, which is high but similar to the results of other studies done in sub-Saharan Africa. Although MA was more common (50%) in individuals with diabetes more than 16 years, a high proportion (42.85%) of patients with MA had a duration of diabetes of ≤ 5years. There was no significant difference in the occurrence of MA with respect to age, gender and duration of diabetes. This study showed a high prevalence of MA in the diabetic population presenting at the Bamenda Regional Hospital. Consequently, measures of glycemic control should be enhanced in this population to prevent the progression to macroalbuminuria and ESRD.},
 year = {2017}
}

Copy | Download

TY - JOUR
T1 - Microalbuminuria in Diabetic Patients in the Bamenda Health District
AU - Marie Ebob Agbortabot Bissong
AU - Gerald Ngo Teke
AU - Moses Samje
AU - Harris Goneh
AU - Frank Eric Tatsing Foka
AU - Henri-Lucien Kamga
Y1 - 2017/10/18
PY - 2017
N1 - https://doi.org/10.11648/j.sjcm.20170604.14
DO - 10.11648/j.sjcm.20170604.14
T2 - Science Journal of Clinical Medicine
JF - Science Journal of Clinical Medicine
JO - Science Journal of Clinical Medicine
SP - 63
EP - 67
PB - Science Publishing Group
SN - 2327-2732
UR - https://doi.org/10.11648/j.sjcm.20170604.14
AB - Diabetic nephropathy (DN) is the most common cause of end stage renal disease (ESRD) and it accounts for one third of all patients requiring renal replacement therapy in Africa. Diabetic patients with microalbuminuria (MA) have an increased risk of progression to macroalbuminuria and later to ESRD. So detecting MA which is a marker of DN helps to alert the clinician to intervene at a time when future renal damage is still preventable. The main goal of this study was to determine the prevalence of MA in diabetic patients at the Bamenda Regional Hospital. This study was a prospective cross sectional study involving diabetic patients at the Bamenda Regional Hospital. A random (spot) or first morning urine specimen was collected and MA was measured by a semi quantitative dipstick method using the URS-14H urine test strips. The prevalence of MA in the present study was 34.6%, which is high but similar to the results of other studies done in sub-Saharan Africa. Although MA was more common (50%) in individuals with diabetes more than 16 years, a high proportion (42.85%) of patients with MA had a duration of diabetes of ≤ 5years. There was no significant difference in the occurrence of MA with respect to age, gender and duration of diabetes. This study showed a high prevalence of MA in the diabetic population presenting at the Bamenda Regional Hospital. Consequently, measures of glycemic control should be enhanced in this population to prevent the progression to macroalbuminuria and ESRD.
VL - 6
IS - 4
ER -

Copy | Download

Author Information

Marie Ebob Agbortabot Bissong

Department of Medical Laboratory Sciences, University of Bamenda, Bambili, Cameroon
Gerald Ngo Teke

Department of Biomedical Sciences, University of Bamenda, Bambili, Cameroon
Moses Samje

Department of Biomedical Sciences, University of Bamenda, Bambili, Cameroon
Harris Goneh

Department of Medical Laboratory Sciences, University of Bamenda, Bambili, Cameroon
Frank Eric Tatsing Foka

Department of Biological Sciences, North West University, Mafikeng, South Africa
Henri-Lucien Kamga

Department of Medical Laboratory Sciences, University of Bamenda, Bambili, Cameroon

Download PDF

Sections

Plain Text BibTeX RIS

APA Style

Marie Ebob Agbortabot Bissong, Gerald Ngo Teke, Moses Samje, Harris Goneh, Frank Eric Tatsing Foka, et al. (2017). Microalbuminuria in Diabetic Patients in the Bamenda Health District. Science Journal of Clinical Medicine, 6(4), 63-67. https://doi.org/10.11648/j.sjcm.20170604.14

Copy | Download

ACS Style

Marie Ebob Agbortabot Bissong; Gerald Ngo Teke; Moses Samje; Harris Goneh; Frank Eric Tatsing Foka, et al. Microalbuminuria in Diabetic Patients in the Bamenda Health District. Sci. J. Clin. Med. 2017, 6(4), 63-67. doi: 10.11648/j.sjcm.20170604.14

Copy | Download

AMA Style

Marie Ebob Agbortabot Bissong, Gerald Ngo Teke, Moses Samje, Harris Goneh, Frank Eric Tatsing Foka, et al. Microalbuminuria in Diabetic Patients in the Bamenda Health District. Sci J Clin Med. 2017;6(4):63-67. doi: 10.11648/j.sjcm.20170604.14

Copy | Download

@article{10.11648/j.sjcm.20170604.14,
  author = {Marie Ebob Agbortabot Bissong and Gerald Ngo Teke and Moses Samje and Harris Goneh and Frank Eric Tatsing Foka and Henri-Lucien Kamga},
  title = {Microalbuminuria in Diabetic Patients in the Bamenda Health District},
  journal = {Science Journal of Clinical Medicine},
  volume = {6},
  number = {4},
  pages = {63-67},
  doi = {10.11648/j.sjcm.20170604.14},
  url = {https://doi.org/10.11648/j.sjcm.20170604.14},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.sjcm.20170604.14},
  abstract = {Diabetic nephropathy (DN) is the most common cause of end stage renal disease (ESRD) and it accounts for one third of all patients requiring renal replacement therapy in Africa. Diabetic patients with microalbuminuria (MA) have an increased risk of progression to macroalbuminuria and later to ESRD. So detecting MA which is a marker of DN helps to alert the clinician to intervene at a time when future renal damage is still preventable. The main goal of this study was to determine the prevalence of MA in diabetic patients at the Bamenda Regional Hospital. This study was a prospective cross sectional study involving diabetic patients at the Bamenda Regional Hospital. A random (spot) or first morning urine specimen was collected and MA was measured by a semi quantitative dipstick method using the URS-14H urine test strips. The prevalence of MA in the present study was 34.6%, which is high but similar to the results of other studies done in sub-Saharan Africa. Although MA was more common (50%) in individuals with diabetes more than 16 years, a high proportion (42.85%) of patients with MA had a duration of diabetes of ≤ 5years. There was no significant difference in the occurrence of MA with respect to age, gender and duration of diabetes. This study showed a high prevalence of MA in the diabetic population presenting at the Bamenda Regional Hospital. Consequently, measures of glycemic control should be enhanced in this population to prevent the progression to macroalbuminuria and ESRD.},
 year = {2017}
}

Copy | Download