Clinical trial was carried out to evaluating the effects of GNRH analogue (buserelin acetate) along with AI in repeat breeding cross breed cows on enhancement of pregnancy. The trial was also aimed at evaluation of dose variation on conception rate. Sixty six cross breed dairy cattle which were apparently healthy, exhibits estrus regularly were selected and assigned randomly in to three equal groups(A,B and C); two treated groups and one control group. Group A (n=22) cattle were injected intramuscularly a 20 µg buserelin acetateat along with AI and Group B (n=22) cattle have injected with dose of 10µg Buserelin acetate. Group C (n=22) cattle were receive no treatment and considered as a control group, given a single service. These cows were examined for pregnancy after three months through rectal palpation. Additional history was taken from herd owners. The pregnancy rates recorded were 68%, 59% and 32% in the cattle grouped with A, B and C respectively. The conception rates of the treated groups exceeds control group by 36% and 27% respectively. Treated groups showed a significant statistical variation (P<0.05) as compared to control group. Dose variation between two treated groups has an effect on pregnancy rate with significant variation. Other observed finding was that treated first and second parity cows became more responsive to therapy than those with more than two parity with a significant variation (P<0.05). The study revealed that the use of GNRH analogue therapy at the time of AI can enhance pregnancy rate. This would be helpful and cost effective to minimize financial losses incurred from milk production loss, managmental and feed cost. This might be achieved through reducing calving interval and treating repeat breeding cases. The benefit cost ratio indicates that individual cow could benefit small holder farmer by 140 USD within a single month.
| Published in | Animal and Veterinary Sciences (Volume 3, Issue 1) |
| DOI | 10.11648/j.avs.20150301.13 |
| Page(s) | 12-17 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2015. Published by Science Publishing Group |
Crossbred Cattle, Estrus, Repeat Breeding GNRH Analogue, Pregnancy Rates
| [1] | Anjum, I. A., Usmani, R. H., Tunio, M. T. and Abro, S. H.(2010). Improvement of Conception rate in Cross Breed Cattle by Using Gonadotropin Releasing Hormone (GNRH) analogue thereapy. Agricultura Tropica et Subtropica, 43:1 |
| [2] | Azage, T., Galal, E. and Beyene, K. (1981).A Study on the reproduction of local zebu andF1cross breeds (European Zebu) Cows, Number of services per conception, gestation length and days open till conception. Ethiopian. J. Agri. Sci 3:1-14. |
| [3] | Azage, T. and Alemu, G. (1998). Prospect for Urban, Periurban dairy development in Ethiopia. Ethiopian Society of Animal production (ESAP), publication no5 Addis Ababa Ethiopia. |
| [4] | Bale, O. (2003). Artificial Insemination Practice in Nigeria, Nigerian Journal of Animal Production. |
| [5] | Banerjee, G. (1998). A Text Book of Animal Husbandry, 8th edition, Oxford and IBH publishing corporation New Delhi |
| [6] | Bearden, J. and Fuquay, W. (1992). Applied Animal Reproduction, 3rd edition Mississippi State University |
| [7] | Beckers, F., Szenci, O., Takacs, E., Sulon, J. and Sousa, N. (2006). Evaluation of GNRH treatment 12 days post A.I in the reproductive performance of dairy cows. Theriogenology. |
| [8] | Blowey, W. (1999). The repeat breeder cow, 3rd edition, A Veterinary Book for Dairy Farmers. |
| [9] | Cam, M. A. – Kuran, M. Yildiz, S. Selcuk, E. 2002. Fetal growth and reproductive performance in ewes administered GNRH agonist on day 12 post-mating. Anim. Reprod. Sci., vol. 72, p. 73-82. |
| [10] | Cline, A. M., (2002). Efficiency of Synthetic Gonadotropin Releasing Hormone analogue for the control of ovulation during estrus synchronization protocols, Animal Science, Physiology of Reproduction. |
| [11] | Connor, O. (2000). Dairy Integrated Reproductive Management, Pennsy State University. |
| [12] | Dougall, S., Williamson, N. and Macmillan, K. (1995). GNRH induces ovulation of dominant follicle in primiparous dairy cows undergoing anovulatory follicle turn over. Anim. Reprod. Sci. 39: 205-214. |
| [13] | Drew, S. and Peters, A. (1994). Veterinary Pharmacology and Therapeutics, Endocrine pharmacology. Vet Rec .134-267. |
| [14] | Ehlers, K., Halvorson, L. and Glob. liber (2013).Gonadotropin Releasing Hormone and Gonadotropin Releasing Hormone Receptors. ISSN, 1756-2228. |
| [15] | FAO. (2000). Food and Agricultural Organization, year book, Rome Italy. |
| [16] | FAO., 2009. Food and Agricultural organization of the United Nations, The State of Food and Agriculture. Livestock, food security and poverty reduction.pp32-50. |
| [17] | Foote, R. (2002). The history of Artificial Insemination, Selected notes and notables, American society of Dairy Sciences |
| [18] | Goley R and Kadu M. (1995). Efficacy of PGF2 α, GNRH and HCG in treatment of repeat breeder cow. Indian Veterinary Journal 72: 472-475. |
| [19] | Gustafsson, H,. Larsso, H, Kindah .and A.Madei. (1986). Sequential Endocrine Changes and Behavior during estrus and met estrus in repeat breeder and virgin heifer’s Anim Repro Sci 10:261. |
| [20] | Hoglund, K. J., (2013), Gene mapping of Reproductive Traits in Cattle, Faculty of Veterinary Medicine and Animal Science, Department of Animal Breeding and Genetics, Uppsala, Sweden |
| [21] | Karg, H., Claus, R., Gunzler, O., Rattenberger, E., Pirchner, F. (1980). Hormonal Recognition of cyclicity and infertility in cows under practical conditions. In proceeding of the 11thWorld congress.Disease of cattle Israel, Pp.885-894. |
| [22] | Karten, M. and River, J. (1986).Endocr Rev.7:44-66.Protective effects of analogs of luteinizing hormone-releasing hormone against chemotherapy-induced testicular damage in rats |
| [23] | Kharche, S. and Srivastava, S. (2007). Dose dependent effect of GNRH analogue on pregnancy rate of repeat breeder cross breed cows. Indian Veterinary Research institute Anim.Repro. Sci. India. |
| [24] | Markandeya, N. (2006). Approaches to enhance conception rate and embryo survivability, Department of Gynecology and Obstetrics Veterinary College, Reproductive Techniques to augment Fertility in dairy animals. Karnataka Veterinary Animal and Fisheries Sciences University. |
| [25] | Mauurer, R. and Echternkamp S. (1985). Repeat breeder Females in Beef cattle Influences and causes, J.Anim Sci, 61:624. |
| [26] | Michael, O, Jeffrey, Stevenson, Brenda, M. and Garth, R. (1993). Administration of GNRH at estrus influences pregnancy rates Serum concentration of LH, FSH estradiol-17 beta, pregnancy specific protein and progesterone, proportion of the luteal cell types and invitro production progesterone in dairy cows. J Anim Sci 71:185-198. |
| [27] | Morgan, W. Lean, I. (1993). Gonadotropin Releasing Hormone treatment in cattle a Meta analysis of effects on conception at the time of insemination. Aust Vet J 70: 205-9. |
| [28] | Morrel, M., (2011). Artificial Insemination; Current and the Future Trends: Swedish University of Agricultural Science, Uppsala, Sweden |
| [29] | MukasaMugaerwa, E., Agaze, T., Tafese, M and Teklu, Y. (1993). Reproductive Efficiency of Bosindicus (Zebu) cows under Artificial Insemination. Anim. Reprod Sci 24: 63-67. |
| [30] | Mwanga, S. E., Zdunczyk, S., and Janowsk, T., (2004). Comparative Efficacy of Hormonal and Non-Hormonal Treatment Methods in Ovarian Afunctions affected dairy cows. |
| [31] | Nagaraja, R. Devaraj, M. (2006). Multi facet Roles of GNRH in Reproduction. Veterinary college, Karnataka Veterinary, animal and Fisheries Sciences University. |
| [32] | Petrie, A. and Watson, P. (2000): Statistics for Veterinary, Revised edition. Blackwel Science Ltd., Osney Mead Oxford OX2 OEL, 25 John Street, London WCIN2 BS. |
| [33] | Schels, H. Mostafawi, D., Morgan, W. (1978). The effect of GNRH on pregnancy rate of artificially inseminated cows.Vet Rec; 103: 31-32. |
| [34] | Sere, C. and Steinfeld, H., 1995.World livestock production system, Current status, Issues and Trends pp6-12. |
| [35] | Stevensen, J, Thompson, W. Forbes, G. Lamb, D. Gerieger, L, Corah. (2000). Synchronizing estrus and ovulation in beef cows after combination of GNRH, norgestment and prostaglandin with or without timed ovulation .J Anim sci, 78:1747-1758. |
| [36] | Stevenson J .Caller, Scoby.and .Phatak. (1990).Double insemination and gonadotropin releasing hormone treatment of repeat breeding dairy cattle J. Dairy Sci 73:1766. |
| [37] | Stojilkovic, S and Catt, K. (1995). Rec. Prog. Horm. Res 50: 161-205. |
| [38] | Srivastava, S.K. and Kharche, S. D. (2002). Effect of GNRH on fertility in crossbred cows. Indian. J. Anim. Sci. 72:428-430. |
| [39] | Tegegn, T., Alemayehu, A. and Ayele, G. (1999). Cross border livestock trade in Southern and south eastern Ethiopia border lines. OSSREA (organization for social science research in eastern and southern Africa) Development Research report series, Commercial printing enterprises. |
| [40] | Thatcher, W. W., M. Drost, J. D. Savio, K. L. Macmillan, K. L. Entwistle, E. J.-P. Schmitt, R. L. de la Sota, and G. R. Morris.1993. New clinical uses for GNRH and its analogues in cattle. Anim. Reprod. Sci. 33:27−49. |
| [41] | Ullah, G., J. W. Fuquay, T. Keawkhong, B. L. Clark, D. E. Pogue,and E. J. Murphey. 1996. Effect gonadotrophin-releasing hormone at estrus on subsequent luteal function and fertility in lactating Holsteins during heat stress. J. Dairy Sci. 79: 1950–1953. |
| [42] | Vishwanath R. (2003). Theriogenology, 59:585-598. |
| [43] | Yemane,B.,Chernet,T.,Shiferaw,T.(1993). Improved Cattle breeding, National Artificial Insemination Center, and Addis Abeba, Ethiopia. |
APA Style
Birhanu Hailu, Berihu Gebrekidan, Solmon Raju, Alemselam Birhanu, Gebrhiwot Tadesse. (2015). Effects of Gonadotropin Releasing Hormone Analogue in Enhancements of Pregnancy in Repeat Breeding Dairy Cows in and around Mekelle, Tigray, Ethiopia. Animal and Veterinary Sciences, 3(1), 12-17. https://doi.org/10.11648/j.avs.20150301.13
ACS Style
Birhanu Hailu; Berihu Gebrekidan; Solmon Raju; Alemselam Birhanu; Gebrhiwot Tadesse. Effects of Gonadotropin Releasing Hormone Analogue in Enhancements of Pregnancy in Repeat Breeding Dairy Cows in and around Mekelle, Tigray, Ethiopia. Anim. Vet. Sci. 2015, 3(1), 12-17. doi: 10.11648/j.avs.20150301.13
AMA Style
Birhanu Hailu, Berihu Gebrekidan, Solmon Raju, Alemselam Birhanu, Gebrhiwot Tadesse. Effects of Gonadotropin Releasing Hormone Analogue in Enhancements of Pregnancy in Repeat Breeding Dairy Cows in and around Mekelle, Tigray, Ethiopia. Anim Vet Sci. 2015;3(1):12-17. doi: 10.11648/j.avs.20150301.13
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Download@article{10.11648/j.avs.20150301.13,
author = {Birhanu Hailu and Berihu Gebrekidan and Solmon Raju and Alemselam Birhanu and Gebrhiwot Tadesse},
title = {Effects of Gonadotropin Releasing Hormone Analogue in Enhancements of Pregnancy in Repeat Breeding Dairy Cows in and around Mekelle, Tigray, Ethiopia},
journal = {Animal and Veterinary Sciences},
volume = {3},
number = {1},
pages = {12-17},
doi = {10.11648/j.avs.20150301.13},
url = {https://doi.org/10.11648/j.avs.20150301.13},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.avs.20150301.13},
abstract = {Clinical trial was carried out to evaluating the effects of GNRH analogue (buserelin acetate) along with AI in repeat breeding cross breed cows on enhancement of pregnancy. The trial was also aimed at evaluation of dose variation on conception rate. Sixty six cross breed dairy cattle which were apparently healthy, exhibits estrus regularly were selected and assigned randomly in to three equal groups(A,B and C); two treated groups and one control group. Group A (n=22) cattle were injected intramuscularly a 20 µg buserelin acetateat along with AI and Group B (n=22) cattle have injected with dose of 10µg Buserelin acetate. Group C (n=22) cattle were receive no treatment and considered as a control group, given a single service. These cows were examined for pregnancy after three months through rectal palpation. Additional history was taken from herd owners. The pregnancy rates recorded were 68%, 59% and 32% in the cattle grouped with A, B and C respectively. The conception rates of the treated groups exceeds control group by 36% and 27% respectively. Treated groups showed a significant statistical variation (P<0.05) as compared to control group. Dose variation between two treated groups has an effect on pregnancy rate with significant variation. Other observed finding was that treated first and second parity cows became more responsive to therapy than those with more than two parity with a significant variation (P<0.05). The study revealed that the use of GNRH analogue therapy at the time of AI can enhance pregnancy rate. This would be helpful and cost effective to minimize financial losses incurred from milk production loss, managmental and feed cost. This might be achieved through reducing calving interval and treating repeat breeding cases. The benefit cost ratio indicates that individual cow could benefit small holder farmer by 140 USD within a single month.},
year = {2015}
}
TY - JOUR T1 - Effects of Gonadotropin Releasing Hormone Analogue in Enhancements of Pregnancy in Repeat Breeding Dairy Cows in and around Mekelle, Tigray, Ethiopia AU - Birhanu Hailu AU - Berihu Gebrekidan AU - Solmon Raju AU - Alemselam Birhanu AU - Gebrhiwot Tadesse Y1 - 2015/01/27 PY - 2015 N1 - https://doi.org/10.11648/j.avs.20150301.13 DO - 10.11648/j.avs.20150301.13 T2 - Animal and Veterinary Sciences JF - Animal and Veterinary Sciences JO - Animal and Veterinary Sciences SP - 12 EP - 17 PB - Science Publishing Group SN - 2328-5850 UR - https://doi.org/10.11648/j.avs.20150301.13 AB - Clinical trial was carried out to evaluating the effects of GNRH analogue (buserelin acetate) along with AI in repeat breeding cross breed cows on enhancement of pregnancy. The trial was also aimed at evaluation of dose variation on conception rate. Sixty six cross breed dairy cattle which were apparently healthy, exhibits estrus regularly were selected and assigned randomly in to three equal groups(A,B and C); two treated groups and one control group. Group A (n=22) cattle were injected intramuscularly a 20 µg buserelin acetateat along with AI and Group B (n=22) cattle have injected with dose of 10µg Buserelin acetate. Group C (n=22) cattle were receive no treatment and considered as a control group, given a single service. These cows were examined for pregnancy after three months through rectal palpation. Additional history was taken from herd owners. The pregnancy rates recorded were 68%, 59% and 32% in the cattle grouped with A, B and C respectively. The conception rates of the treated groups exceeds control group by 36% and 27% respectively. Treated groups showed a significant statistical variation (P<0.05) as compared to control group. Dose variation between two treated groups has an effect on pregnancy rate with significant variation. Other observed finding was that treated first and second parity cows became more responsive to therapy than those with more than two parity with a significant variation (P<0.05). The study revealed that the use of GNRH analogue therapy at the time of AI can enhance pregnancy rate. This would be helpful and cost effective to minimize financial losses incurred from milk production loss, managmental and feed cost. This might be achieved through reducing calving interval and treating repeat breeding cases. The benefit cost ratio indicates that individual cow could benefit small holder farmer by 140 USD within a single month. VL - 3 IS - 1 ER -
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