Pituitary Gland Assessment by MR Volumetry in the Normal Indian Adolescent Population

Deepti Naik; Prashanth Reddy D.; M. G. Srinath; A. Ashok Kumar

doi:doi:10.11648/j.ijmi.20150306.11

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Pituitary Gland Assessment by MR Volumetry in the Normal Indian Adolescent Population

Deepti Naik, Prashanth Reddy D., M. G. Srinath, A. Ashok Kumar

Published in International Journal of Medical Imaging (Volume 3, Issue 6)

Received: 10 October 2015 Accepted: 24 October 2015 Published: 3 November 2015

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Abstract

The purpose of the study was to analyze the shapes and volumes of the pituitary gland as seen on magnetic resonance imaging using two different methods in the adolescent age group (10 to 19 years). The study was designed as a retrospective review. MRI brain was performed in 99 patients and pituitary volumes were calculated using voxel counting method and the ellipsoid formula. Pituitary shape was graded from one to five based on the surface curvature. The volume, height and shape of the pituitary in male and female patients were analyzed. The average pituitary volume by voxel counting method was found to be 0.54 cc ± 0.16 cc in both sexes, 0.51 ± 0.13 cc in males and 0.56 ± 0.19 cc in females. The average pituitary volume by ROI was found to be 0.42 cc ± 0.16 cc in both sexes, 0.40cc ± 0.15 cc in males and 0.43 cc ± 0.17 cc in females. The average pituitary height was 0.58 cm ± 0.15 cm in both sexes, 0.55 cm ± 0.16 cm in males and 0.60 cm ± 0.15 cm in females. The correlation coefficients between the two methods for concave shapes, for flat shapes and for convex shapes were 0.73, 0.76 and 0.60 with p values were 0.0007, 0.0007 and 0.0002 respectively. The average volume of the pituitary gland was 6% greater in females. There was a gradual increase in volume and height of pituitary gland with age. The two methods showed positive correlation which was statistically significant.

Published in	International Journal of Medical Imaging (Volume 3, Issue 6)
DOI	10.11648/j.ijmi.20150306.11
Page(s)	105-109
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2015. Published by Science Publishing Group

Keywords

Pituitary Gland Assessment, Volumetry, Adolescent

References

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[2]	Lurie SN, Doraiswamy PM, Husain MM, et al. In vivo assessment of pituitary gland volume with magnetic resonance imaging: the effect of age. J Clin Endocrinol Metab 1990; 71:505-508.
[3]	Gonzalez JG, Elizondo G, Saldivar D, Nanez H, Todd L, Villarreal JZ. Pituitary gland growth during normal pregnancy: an in vivo study using magnetic resonance imaging. Am J Med 1988; 85:217-220.
[4]	Krishnan KRR, Doraiswamy PM, Lurie SN, et al. Pituitary size in depression. J Clin Endocrinol Metab 1991; 72:256-259.
[5]	Sharafuddin MJA, Luisiri A, Garibaldi LR, et al. MR imaging diagnosis of central precocious puberty: importance of changes in the shape and size of the pituitary gland. AJR Am J Roentgenol 1994; 162:1167-1173.
[6]	Fink AM, Vidmar S, Kumbla S, et al. Age-related pituitary volumes in prepubertal children with normal endocrine function: volumetric magnetic resonance data. J Clin Endocrinol Metab. 2005 Jun; 90(6):3274-8.
[7]	Miyuki Takasu, Chihiro Tani, Yoko Kaichi et al.Pituitary Volumes and Functions in Children with Growth Hormon Deficiency: Volumetric Magnetic Resonance Findings. Journal of Endocrinology and Diabetes Mellitus, 2014, 2, 39-44.
[8]	Ibinaiye PO, Olarinoye-Akorede S, Kajogbola O, Bakari AG. Magnetic Resonance Imaging Determination of Normal Pituitary Gland Dimensions in Zaria, Northwest Nigerian Population. Journal of Clinical Imaging Science. 2015; 5:29.
[9]	Koichi T, Hidetsuna U, Hiroyuki O et al.Normal Development of the Pituitary Gland: Assessment with Three-dimensional MR Volumetry. AJNR 1999 20: 312-315.
[10]	Ikram MF, Sajjad Z, Shokh IS, Omair A. Pituitary height on magnetic resonance imaging observation of age and sex related changes. J Pak Med Assoc. 2008; 58:261–5.
[11]	Denk CC, Onderoğlu S, Ilgi S, Gürcan F. Height of normal pituitary gland on MRI: Differences between age groups and sexes. Okajimas Folia Anat Jpn. 1999; 76:81.
[12]	Takano K, Utsunomiya H, Ono H, Ohfu M, Okazaki M 1999 Normal development of the pituitary gland: assessment with three-dimensional MR volumetry. AJNR Am J Neuroradiol 20:312–315.
[13]	Suzuki M, Takashima T, Kadoya M, Konishi H, Kameyama T, Yoshikawa J, et al. Height of normal pituitary gland on MR imaging: Age and sex differentiation. J Comput Assist Tomogr. 1990; 14:36–9.
[14]	Argyropoulou M, Perignon F, Brunelle F, Brauner R, Rappaport R. Height of normal pituitary gland as a function of age evaluated by magnetic resonance imaging in children. Pediatr Radiol. 1991; 21:247–9.
[15]	Kato K, Saeki N, Yamaura A. Morphological changes on MR imaging of the normal pituitary gland related to age and sex: Main emphasis on pubescent females. J Clin Neurosci. 2002; 9:53–6.
[16]	Doraiswamy PM, Potts JM, Axelson DA, et al. MR assessment of pituitary gland morphology in healthy volunteers: Age- and gender-related differences. AJNR Am J Neurodiol. 1992; 13:1295–9.

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APA Style

Deepti Naik, Prashanth Reddy D., M. G. Srinath, A. Ashok Kumar. (2015). Pituitary Gland Assessment by MR Volumetry in the Normal Indian Adolescent Population. International Journal of Medical Imaging, 3(6), 105-109. https://doi.org/10.11648/j.ijmi.20150306.11

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ACS Style

Deepti Naik; Prashanth Reddy D.; M. G. Srinath; A. Ashok Kumar. Pituitary Gland Assessment by MR Volumetry in the Normal Indian Adolescent Population. Int. J. Med. Imaging 2015, 3(6), 105-109. doi: 10.11648/j.ijmi.20150306.11

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AMA Style

Deepti Naik, Prashanth Reddy D., M. G. Srinath, A. Ashok Kumar. Pituitary Gland Assessment by MR Volumetry in the Normal Indian Adolescent Population. Int J Med Imaging. 2015;3(6):105-109. doi: 10.11648/j.ijmi.20150306.11

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@article{10.11648/j.ijmi.20150306.11,
  author = {Deepti Naik and Prashanth Reddy D. and M. G. Srinath and A. Ashok Kumar},
  title = {Pituitary Gland Assessment by MR Volumetry in the Normal Indian Adolescent Population},
  journal = {International Journal of Medical Imaging},
  volume = {3},
  number = {6},
  pages = {105-109},
  doi = {10.11648/j.ijmi.20150306.11},
  url = {https://doi.org/10.11648/j.ijmi.20150306.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijmi.20150306.11},
  abstract = {The purpose of the study was to analyze the shapes and volumes of the pituitary gland as seen on magnetic resonance imaging using two different methods in the adolescent age group (10 to 19 years). The study was designed as a retrospective review. MRI brain was performed in 99 patients and pituitary volumes were calculated using voxel counting method and the ellipsoid formula. Pituitary shape was graded from one to five based on the surface curvature. The volume, height and shape of the pituitary in male and female patients were analyzed. The average pituitary volume by voxel counting method was found to be 0.54 cc ± 0.16 cc in both sexes, 0.51 ± 0.13 cc in males and 0.56 ± 0.19 cc in females. The average pituitary volume by ROI was found to be 0.42 cc ± 0.16 cc in both sexes, 0.40cc ± 0.15 cc in males and 0.43 cc ± 0.17 cc in females. The average pituitary height was 0.58 cm ± 0.15 cm in both sexes, 0.55 cm ± 0.16 cm in males and 0.60 cm ± 0.15 cm in females. The correlation coefficients between the two methods for concave shapes, for flat shapes and for convex shapes were 0.73, 0.76 and 0.60 with p values were 0.0007, 0.0007 and 0.0002 respectively. The average volume of the pituitary gland was 6% greater in females. There was a gradual increase in volume and height of pituitary gland with age. The two methods showed positive correlation which was statistically significant.},
 year = {2015}
}

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TY - JOUR
T1 - Pituitary Gland Assessment by MR Volumetry in the Normal Indian Adolescent Population
AU - Deepti Naik
AU - Prashanth Reddy D.
AU - M. G. Srinath
AU - A. Ashok Kumar
Y1 - 2015/11/03
PY - 2015
N1 - https://doi.org/10.11648/j.ijmi.20150306.11
DO - 10.11648/j.ijmi.20150306.11
T2 - International Journal of Medical Imaging
JF - International Journal of Medical Imaging
JO - International Journal of Medical Imaging
SP - 105
EP - 109
PB - Science Publishing Group
SN - 2330-832X
UR - https://doi.org/10.11648/j.ijmi.20150306.11
AB - The purpose of the study was to analyze the shapes and volumes of the pituitary gland as seen on magnetic resonance imaging using two different methods in the adolescent age group (10 to 19 years). The study was designed as a retrospective review. MRI brain was performed in 99 patients and pituitary volumes were calculated using voxel counting method and the ellipsoid formula. Pituitary shape was graded from one to five based on the surface curvature. The volume, height and shape of the pituitary in male and female patients were analyzed. The average pituitary volume by voxel counting method was found to be 0.54 cc ± 0.16 cc in both sexes, 0.51 ± 0.13 cc in males and 0.56 ± 0.19 cc in females. The average pituitary volume by ROI was found to be 0.42 cc ± 0.16 cc in both sexes, 0.40cc ± 0.15 cc in males and 0.43 cc ± 0.17 cc in females. The average pituitary height was 0.58 cm ± 0.15 cm in both sexes, 0.55 cm ± 0.16 cm in males and 0.60 cm ± 0.15 cm in females. The correlation coefficients between the two methods for concave shapes, for flat shapes and for convex shapes were 0.73, 0.76 and 0.60 with p values were 0.0007, 0.0007 and 0.0002 respectively. The average volume of the pituitary gland was 6% greater in females. There was a gradual increase in volume and height of pituitary gland with age. The two methods showed positive correlation which was statistically significant.
VL - 3
IS - 6
ER -

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Author Information

Deepti Naik

Department of Radiodiagnosis and Imaging, M.S. Ramaiah Medical College & Hospitals, Bangalore, India
Prashanth Reddy D.

Department of Radiodiagnosis and Imaging, M.S. Ramaiah Medical College & Hospitals, Bangalore, India
M. G. Srinath

Department of Radiodiagnosis and Imaging, M.S. Ramaiah Medical College & Hospitals, Bangalore, India
A. Ashok Kumar

Department of Radiodiagnosis and Imaging, M.S. Ramaiah Medical College & Hospitals, Bangalore, India

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APA Style

Deepti Naik, Prashanth Reddy D., M. G. Srinath, A. Ashok Kumar. (2015). Pituitary Gland Assessment by MR Volumetry in the Normal Indian Adolescent Population. International Journal of Medical Imaging, 3(6), 105-109. https://doi.org/10.11648/j.ijmi.20150306.11

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ACS Style

Deepti Naik; Prashanth Reddy D.; M. G. Srinath; A. Ashok Kumar. Pituitary Gland Assessment by MR Volumetry in the Normal Indian Adolescent Population. Int. J. Med. Imaging 2015, 3(6), 105-109. doi: 10.11648/j.ijmi.20150306.11

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AMA Style

Deepti Naik, Prashanth Reddy D., M. G. Srinath, A. Ashok Kumar. Pituitary Gland Assessment by MR Volumetry in the Normal Indian Adolescent Population. Int J Med Imaging. 2015;3(6):105-109. doi: 10.11648/j.ijmi.20150306.11

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@article{10.11648/j.ijmi.20150306.11,
  author = {Deepti Naik and Prashanth Reddy D. and M. G. Srinath and A. Ashok Kumar},
  title = {Pituitary Gland Assessment by MR Volumetry in the Normal Indian Adolescent Population},
  journal = {International Journal of Medical Imaging},
  volume = {3},
  number = {6},
  pages = {105-109},
  doi = {10.11648/j.ijmi.20150306.11},
  url = {https://doi.org/10.11648/j.ijmi.20150306.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijmi.20150306.11},
  abstract = {The purpose of the study was to analyze the shapes and volumes of the pituitary gland as seen on magnetic resonance imaging using two different methods in the adolescent age group (10 to 19 years). The study was designed as a retrospective review. MRI brain was performed in 99 patients and pituitary volumes were calculated using voxel counting method and the ellipsoid formula. Pituitary shape was graded from one to five based on the surface curvature. The volume, height and shape of the pituitary in male and female patients were analyzed. The average pituitary volume by voxel counting method was found to be 0.54 cc ± 0.16 cc in both sexes, 0.51 ± 0.13 cc in males and 0.56 ± 0.19 cc in females. The average pituitary volume by ROI was found to be 0.42 cc ± 0.16 cc in both sexes, 0.40cc ± 0.15 cc in males and 0.43 cc ± 0.17 cc in females. The average pituitary height was 0.58 cm ± 0.15 cm in both sexes, 0.55 cm ± 0.16 cm in males and 0.60 cm ± 0.15 cm in females. The correlation coefficients between the two methods for concave shapes, for flat shapes and for convex shapes were 0.73, 0.76 and 0.60 with p values were 0.0007, 0.0007 and 0.0002 respectively. The average volume of the pituitary gland was 6% greater in females. There was a gradual increase in volume and height of pituitary gland with age. The two methods showed positive correlation which was statistically significant.},
 year = {2015}
}

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